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| 23.01.2016 | 20:00 | AFC Tubize | - | KSV Roeselare | 0:1 (0:0) | |
| 20:00 | White Star Bruxelles | - | Royal Antwerp FC | 0:4 (0:2) | ||
| 20:00 | RFC Seraing | - | SK Deinze | 1:5 (0:2) | ||
| 20:00 | KSK Heist | - | KVV Coxyde | 3:0 (1:0) | ||
| 20:00 | Patro Eisden MM | - | Union Saint-Gilloise | 2:1 (0:0) | ||
| 20:00 | Excelsior Virton | - | Lommel United | 1:2 (0:1) | ||
| 20:00 | Lierse SK | - | KAS Eupen | 1:1 (1:0) | ||
| 20:00 | ASV Geel | - | Cercle Brugge | 3:3 (2:1) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Royal Antwerp FC | 20 | 13 | 6 | 1 | 38:10 | 28 | 45 |
| 2 |
|
AFC Tubize | 21 | 12 | 3 | 6 | 33:20 | 13 | 39 |
| 3 |
|
Union Saint-Gilloise | 20 | 12 | 2 | 6 | 36:20 | 16 | 38 |
| 4 |
|
White Star Bruxelles | 21 | 11 | 5 | 5 | 35:20 | 15 | 38 |
| 5 |
|
KSV Roeselare | 21 | 11 | 5 | 5 | 35:29 | 6 | 38 |
| 6 |
|
Cercle Brugge | 20 | 10 | 7 | 3 | 40:21 | 19 | 37 |
| 7 |
|
KAS Eupen | 21 | 10 | 6 | 5 | 43:24 | 19 | 36 |
| 8 |
|
Lommel United | 21 | 10 | 5 | 6 | 32:17 | 15 | 35 |
| 9 |
|
Lierse SK | 21 | 7 | 7 | 7 | 34:32 | 2 | 28 |
| 10 |
|
RFC Seraing | 21 | 8 | 3 | 10 | 28:39 | -11 | 27 |
| 11 |
|
Excelsior Virton | 21 | 6 | 6 | 9 | 26:36 | -10 | 24 |
| 12 |
|
KFC Dessel Sport | 20 | 6 | 6 | 8 | 19:32 | -13 | 24 |
| 13 |
|
SK Deinze | 21 | 4 | 7 | 10 | 27:42 | -15 | 19 |
| 14 |
|
ASV Geel | 21 | 2 | 11 | 8 | 28:40 | -12 | 17 |
| 15 |
|
Patro Eisden MM | 21 | 3 | 7 | 11 | 21:40 | -19 | 16 |
| 16 |
|
KSK Heist | 21 | 2 | 5 | 14 | 29:55 | -26 | 11 |
| 17 |
|
KVV Coxyde | 20 | 0 | 7 | 13 | 17:44 | -27 | 7 |
| Promotion | |
| Relégation |
