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| H (Match allé) | Athletico Paranaense | - | Santos FC | 3:2 (2:2) | ||
| R (match retour) | Santos FC | - | Athletico Paranaense | 0:2 (0:1) | ||
| H (Match allé): 02.06.2005 00:15 | R (match retour): 16.06.2005 03:00 | vainqueur: Athletico Paranaense | ||||
| H (Match allé) | São Paulo FC | - | UANL Tigres | 4:0 (2:0) | ||
| R (match retour) | UANL Tigres | - | São Paulo FC | 2:1 (0:0) | ||
| H (Match allé): 02.06.2005 02:45 | R (match retour): 16.06.2005 03:00 | vainqueur: São Paulo FC | ||||
| H (Match allé) | Banfield | - | River Plate | 1:1 (0:1) | ||
| R (match retour) | River Plate | - | Banfield | 3:2 (3:1) | ||
| H (Match allé): 03.06.2005 01:00 | R (match retour): 17.06.2005 01:30 | vainqueur: River Plate | ||||
| H (Match allé) | Deportivo Guadalajara | - | Boca Juniors | 4:0 (0:0) | ||
| R (match retour) | Boca Juniors | - | Deportivo Guadalajara | interrompu | ||
| H (Match allé): 03.06.2005 03:30 | R (match retour): 15.06.2005 02:15 | vainqueur: Deportivo Guadalajara | ||||
