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| 01.04.2006 | 14:25 | Slavia Praha | - | FK SIAD Most | 3:0 (1:0) | |
| 18:00 | Baník Ostrava | - | 1. FC Slovácko | 2:0 (1:0) | ||
| 02.04.2006 | 15:00 | Chmel Blsany | - | AC Sparta Praha | 0:0 (0:0) | |
| 17:00 | FK Jablonec 97 | - | 1. FC Brno | 0:2 (0:1) | ||
| 17:00 | Viktoria Plzeň | - | FK Mladá Boleslav | 0:1 (0:0) | ||
| 17:00 | Tescoma Zlín | - | FK Marila Příbram | 1:0 (0:0) | ||
| 17:00 | FK Teplice | - | Vysočina Jihlava | 3:1 (2:0) | ||
| 03.04.2006 | 16:40 | Sigma Olomouc | - | Slovan Liberec | 1:0 (1:0) |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Slovan Liberec | 23 | 14 | 7 | 2 | 33:14 | 19 | 49 |
| 2 |
|
Slavia Praha | 23 | 11 | 8 | 4 | 41:27 | 14 | 41 |
| 3 |
|
FK Teplice | 23 | 10 | 11 | 2 | 30:18 | 12 | 41 |
| 4 |
|
FK Mladá Boleslav | 23 | 11 | 6 | 6 | 35:28 | 7 | 39 |
| 5 |
|
AC Sparta Praha | 23 | 9 | 5 | 9 | 32:30 | 2 | 32 |
| 6 |
|
FK Jablonec 97 | 23 | 9 | 5 | 9 | 31:29 | 2 | 32 |
| 7 |
|
Tescoma Zlín | 23 | 8 | 7 | 8 | 21:23 | -2 | 31 |
| 8 |
|
Sigma Olomouc | 23 | 9 | 4 | 10 | 28:33 | -5 | 31 |
| 9 |
|
FK Marila Příbram | 23 | 6 | 9 | 8 | 30:28 | 2 | 27 |
| 10 |
|
FK SIAD Most | 23 | 8 | 3 | 12 | 22:31 | -9 | 27 |
| 11 |
|
1. FC Brno | 23 | 5 | 11 | 7 | 23:24 | -1 | 26 |
| 12 |
|
Baník Ostrava | 23 | 6 | 8 | 9 | 21:25 | -4 | 26 |
| 13 |
|
Viktoria Plzeň | 23 | 5 | 9 | 9 | 24:28 | -4 | 24 |
| 14 |
|
1. FC Slovácko | 23 | 5 | 8 | 10 | 21:27 | -6 | 23 |
| 15 |
|
Chmel Blsany | 23 | 4 | 10 | 9 | 16:30 | -14 | 22 |
| 16 |
|
Vysočina Jihlava | 23 | 4 | 9 | 10 | 14:27 | -13 | 21 |
| Champions League Quali. | |
| Europa League Quali. | |
| Relégation |
