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| 08.04.2011 | 20:15 | Viktoria Plzeň | - | FK Baumit Jablonec | 1:1 (0:0) | |
| 09.04.2011 | 16:00 | Slovan Liberec | - | Sigma Olomouc | 3:0 (1:0) | |
| 18:00 | 1. FC Slovácko | - | 1. FK Příbram | 2:0 (0:0) | ||
| 19:00 | FK Teplice | - | FK Mladá Boleslav | 1:2 (1:1) | ||
| 10.04.2011 | 17:00 | Dynamo České Budějovice | - | FK Ústí nad Labem | 2:0 (2:0) | |
| 17:00 | FC Hradec Králové | - | Baník Ostrava | 2:1 (1:1) | ||
| 17:00 | Bohemians 1905 | - | Zbrojovka Brno | 2:1 (2:0) | ||
| 11.04.2011 | 20:00 | AC Sparta Praha | - | Slavia Praha | 2:0 (2:0) |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Viktoria Plzeň | 23 | 17 | 4 | 2 | 56:21 | 35 | 55 |
| 2 |
|
AC Sparta Praha | 23 | 16 | 1 | 6 | 37:14 | 23 | 49 |
| 3 |
|
FK Baumit Jablonec | 23 | 13 | 5 | 5 | 46:22 | 24 | 44 |
| 4 |
|
FK Mladá Boleslav | 23 | 11 | 7 | 5 | 40:27 | 13 | 40 |
| 5 |
|
Sigma Olomouc | 23 | 11 | 5 | 7 | 39:21 | 18 | 38 |
| 6 |
|
FK Teplice | 23 | 10 | 5 | 8 | 33:32 | 1 | 35 |
| 7 |
|
Bohemians 1905 | 23 | 10 | 5 | 8 | 27:24 | 3 | 35 |
| 8 |
|
Slovan Liberec | 23 | 8 | 6 | 9 | 31:27 | 4 | 30 |
| 9 |
|
FC Hradec Králové | 23 | 7 | 7 | 9 | 19:30 | -11 | 28 |
| 10 |
|
1. FC Slovácko | 23 | 7 | 5 | 11 | 23:35 | -12 | 26 |
| 11 |
|
Slavia Praha | 23 | 5 | 10 | 8 | 25:29 | -4 | 25 |
| 12 |
|
Dynamo České Budějovice | 23 | 5 | 9 | 9 | 19:35 | -16 | 24 |
| 13 |
|
Baník Ostrava | 23 | 6 | 5 | 12 | 21:33 | -12 | 23 |
| 14 |
|
1. FK Příbram | 23 | 5 | 7 | 11 | 13:25 | -12 | 22 |
| 15 |
|
Zbrojovka Brno | 23 | 6 | 1 | 16 | 26:46 | -20 | 19 |
| 16 |
|
FK Ústí nad Labem | 23 | 3 | 6 | 14 | 16:50 | -34 | 15 |
| Champions League Quali. | |
| Europa League | |
| Relégation |
