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| 01.11.2008 | 20:00 | Málaga CF | - | FC Barcelona | 1:4 (1:2) | |
| 20:00 | Athletic Bilbao | - | Villarreal CF | 1:4 (1:1) | ||
| 20:00 | Atlético Madrid | - | RCD Mallorca | 2:0 (2:0) | ||
| 22:00 | Valencia CF | - | Racing Santander | 2:4 (1:1) | ||
| 02.11.2008 | 17:00 | Recreativo Huelva | - | Getafe CF | 1:1 (0:0) | |
| 17:00 | Real Valladolid | - | Sevilla FC | 3:2 (1:2) | ||
| 17:00 | Espanyol Barcelona | - | CA Osasuna | 1:0 (0:0) | ||
| 17:00 | Sporting Gijón | - | CD Numancia | 3:1 (1:1) | ||
| 19:00 | UD Almería | - | Real Madrid | 1:1 (0:1) | ||
| 21:00 | Real Betis | - | Deportivo La Coruña | 0:3 (0:0) |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Barcelona | 9 | 7 | 1 | 1 | 28:8 | 20 | 22 |
| 2 |
|
Villarreal CF | 9 | 6 | 3 | 0 | 17:8 | 9 | 21 |
| 3 |
|
Real Madrid | 9 | 6 | 2 | 1 | 24:13 | 11 | 20 |
| 4 |
|
Valencia CF | 9 | 6 | 2 | 1 | 20:9 | 11 | 20 |
| 5 |
|
Sevilla FC | 9 | 5 | 2 | 2 | 15:8 | 7 | 17 |
| 6 |
|
Atlético Madrid | 9 | 4 | 1 | 4 | 19:16 | 3 | 13 |
| 7 |
|
Getafe CF | 9 | 3 | 4 | 2 | 10:9 | 1 | 13 |
| 8 |
|
Málaga CF | 9 | 4 | 1 | 4 | 10:13 | -3 | 13 |
| 9 |
|
Deportivo La Coruña | 9 | 3 | 3 | 3 | 8:9 | -1 | 12 |
| 10 |
|
Espanyol Barcelona | 9 | 3 | 3 | 3 | 7:10 | -3 | 12 |
| 11 |
|
UD Almería | 9 | 3 | 3 | 3 | 10:14 | -4 | 12 |
| 12 |
|
Sporting Gijón | 9 | 4 | 0 | 5 | 16:22 | -6 | 12 |
| 13 |
|
RCD Mallorca | 9 | 3 | 2 | 4 | 8:12 | -4 | 11 |
| 14 |
|
Real Valladolid | 9 | 3 | 1 | 5 | 9:11 | -2 | 10 |
| 15 |
|
Racing Santander | 9 | 2 | 3 | 4 | 9:12 | -3 | 9 |
| 16 |
|
Real Betis | 9 | 2 | 2 | 5 | 9:11 | -2 | 8 |
| 17 |
|
CD Numancia | 9 | 2 | 1 | 6 | 8:17 | -9 | 7 |
| 18 |
|
Recreativo Huelva | 9 | 1 | 4 | 4 | 5:14 | -9 | 7 |
| 19 |
|
Athletic Bilbao | 9 | 1 | 2 | 6 | 7:17 | -10 | 5 |
| 20 |
|
CA Osasuna | 9 | 0 | 4 | 5 | 3:9 | -6 | 4 |
| Champions League | |
| Champions League Quali. | |
| Europa League | |
| Relégation |
