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| 01.10.2017 | 12:00 | Lorca Deportiva | - | UD Melilla | 0:0 (0:0) | |
| 12:00 | FC Jumilla | - | Marbella FC | 1:1 (0:1) | ||
| 12:00 | UD Las Palmas B | - | San Fernando CD | 0:1 (0:0) | ||
| 17:00 | Real Betis B | - | UCAM Murcia CF | 1:0 (1:0) | ||
| 18:00 | CD Badajoz | - | CF Villanovense | 1:1 (0:0) | ||
| 18:00 | Real Murcia | - | Mérida AD | 1:1 (1:0) | ||
| 18:00 | Extremadura UD | - | Granada CF B | 1:0 (1:0) | ||
| 18:30 | Écija Balompié | - | Recreativo Huelva | 0:0 (0:0) | ||
| 18:30 | RB Linense | - | CD El Ejido 2012 | 2:0 (1:0) | ||
| 19:00 | FC Cartagena | - | Córdoba CF B | 0:0 (0:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Écija Balompié | 7 | 4 | 3 | 0 | 10:5 | 5 | 15 |
| 2 |
|
RB Linense | 7 | 4 | 2 | 1 | 12:4 | 8 | 14 |
| 3 |
|
Extremadura UD | 7 | 4 | 2 | 1 | 9:5 | 4 | 14 |
| 4 |
|
Granada CF B | 7 | 4 | 1 | 2 | 7:4 | 3 | 13 |
| 5 |
|
UCAM Murcia CF | 7 | 4 | 1 | 2 | 8:7 | 1 | 13 |
| 6 |
|
FC Cartagena | 7 | 3 | 3 | 1 | 11:8 | 3 | 12 |
| 7 |
|
UD Melilla | 7 | 3 | 3 | 1 | 9:3 | 6 | 12 |
| 8 |
|
Mérida AD | 7 | 3 | 2 | 2 | 10:7 | 3 | 11 |
| 9 |
|
Marbella FC | 7 | 3 | 2 | 2 | 6:6 | 0 | 11 |
| 10 |
|
Real Betis B | 7 | 3 | 1 | 3 | 11:13 | -2 | 10 |
| 11 |
|
CF Villanovense | 7 | 2 | 3 | 2 | 8:6 | 2 | 9 |
| 12 |
|
Recreativo Huelva | 7 | 1 | 5 | 1 | 7:7 | 0 | 8 |
| 13 |
|
Real Murcia | 7 | 1 | 4 | 2 | 8:7 | 1 | 7 |
| 14 |
|
Córdoba CF B | 7 | 1 | 4 | 2 | 5:6 | -1 | 7 |
| 15 |
|
CD El Ejido 2012 | 7 | 1 | 3 | 3 | 10:13 | -3 | 6 |
| 16 |
|
CD Badajoz | 7 | 0 | 5 | 2 | 6:9 | -3 | 5 |
| 17 |
|
San Fernando CD | 7 | 1 | 2 | 4 | 5:10 | -5 | 5 |
| 18 |
|
FC Jumilla | 7 | 0 | 4 | 3 | 5:9 | -4 | 4 |
| 19 |
|
UD Las Palmas B | 7 | 1 | 1 | 5 | 5:12 | -7 | 4 |
| 20 |
|
Lorca Deportiva | 7 | 0 | 3 | 4 | 4:15 | -11 | 3 |
| Play-off | |
| Play-off | |
| Relégation | |
| Relégation |
