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| H (Match allé) | Lazio Roma | - | Inter | 1:1 (1:1) | ||
| R (match retour) | Inter | - | Lazio Roma | 1:0 (1:0) | ||
| H (Match allé): 24.01.2006 21:00 | R (match retour): 02.02.2006 21:00 | vainqueur: Inter | ||||
| H (Match allé) | Udinese Calcio | - | Sampdoria | 1:1 (1:0) | ||
| R (match retour) | Sampdoria | - | Udinese Calcio | 2:2 (0:1) | ||
| H (Match allé): 25.01.2006 18:00 | R (match retour): 01.02.2006 17:30 | vainqueur: Udinese Calcio | ||||
| H (Match allé) | AC Milan | - | US Palermo | 1:0 (0:0) | ||
| R (match retour) | US Palermo | - | AC Milan | 3:0 (2:0) | ||
| H (Match allé): 25.01.2006 21:00 | R (match retour): 31.01.2006 21:00 | vainqueur: US Palermo | ||||
| H (Match allé) | Juventus | - | AS Roma | 2:3 (0:1) | ||
| R (match retour) | AS Roma | - | Juventus | 0:1 (0:0) | ||
| H (Match allé): 26.01.2006 21:00 | R (match retour): 01.02.2006 21:00 | vainqueur: AS Roma | ||||
