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| 08.03.2019 | 22:00 | Cruz Azul Hidalgo | - | Deportivo Toluca II | 1:1 (0:0) | |
| 09.03.2019 | 00:20 | Murciélagos FC | - | Atlético Reynosa | 1:1 (0:0) | |
| 01:00 | Tecos Fútbol Club | - | Correcaminos UAT II | 3:3 (1:2) | ||
| 19:00 | Monarcas Morelia II | - | Alacranes de Durango | 1:1 (0:0) | ||
| 22:00 | Real Zamora | - | Pumas UNAM II | 2:4 (1:0) | ||
| 22:30 | Tuzos de la UAZ | - | Inter Playa | 1:2 (1:1) | ||
| 23:00 | Gavilanes de Matamoros | - | Pacific F. C. | 3:1 (2:1) | ||
| 23:00 | Sporting Canamy | - | CF América II | 1:2 (1:1) | ||
| 23:00 | Tepatitlán | - | Dorados UACH | 3:2 (1:0) | ||
| 23:00 | Yalmakan FC | - | Pioneros de Cancún | 1:1 (0:0) | ||
| 23:00 | Cocodrilos de Tabasco | - | Albinegros Orizaba | 1:0 (0:0) | ||
| 10.03.2019 | 02:00 | Club Irapuato | - | Tuxtla FC | 2:0 (1:0) | |
| 03:00 | Reboceros de La Piedad | - | Coyotes de Tlaxcala | 1:0 (1:0) | ||
| 18:00 | Club Necaxa II | - | Coras de Nayarit | 1:0 (0:0) | ||
| 19:00 | Leones Negros II | - | Loros UCOL | 3:2 (2:0) | ||
| 12.03.2019 | 00:00 | Cimarrones de Sonora II | - | Deportivo Guadalajara II | 0:1 (0:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Club Irapuato | 24 | 18 | 4 | 2 | 44:14 | 30 | 62 |
| 2 |
|
Deportivo Guadalajara II | 24 | 13 | 8 | 3 | 36:23 | 13 | 51 |
| 3 |
|
Loros UCOL | 24 | 13 | 4 | 7 | 60:28 | 32 | 49 |
| 4 |
|
Tepatitlán | 24 | 13 | 6 | 5 | 42:30 | 12 | 47 |
| 5 |
|
Club Necaxa II | 24 | 12 | 7 | 5 | 29:23 | 6 | 46 |
| 6 |
|
Murciélagos FC | 24 | 12 | 5 | 7 | 42:25 | 17 | 44 |
| 7 |
|
Pumas UNAM II | 24 | 12 | 5 | 7 | 36:26 | 10 | 44 |
| 8 |
|
Tuxtla FC | 24 | 12 | 4 | 8 | 37:24 | 13 | 42 |
| 9 |
|
Atlético Reynosa | 24 | 10 | 8 | 6 | 31:18 | 13 | 42 |
| 10 |
|
Tuzos de la UAZ | 24 | 10 | 8 | 6 | 35:30 | 5 | 40 |
| 11 |
|
Dorados UACH | 24 | 10 | 6 | 8 | 27:24 | 3 | 40 |
| 12 |
|
Coras de Nayarit | 24 | 10 | 7 | 7 | 31:26 | 5 | 39 |
| 13 |
|
Deportivo Toluca II | 24 | 10 | 7 | 7 | 35:31 | 4 | 39 |
| 14 |
|
Real Zamora | 24 | 11 | 4 | 9 | 33:31 | 2 | 39 |
| 15 |
|
Gavilanes de Matamoros | 24 | 10 | 6 | 8 | 34:28 | 6 | 38 |
| 16 |
|
Cruz Azul Hidalgo | 24 | 9 | 6 | 9 | 28:27 | 1 | 37 |
| 17 |
|
Inter Playa | 24 | 9 | 7 | 8 | 28:26 | 2 | 36 |
| 18 |
|
Monarcas Morelia II | 24 | 8 | 9 | 7 | 41:27 | 14 | 34 |
| 19 |
|
Correcaminos UAT II | 24 | 8 | 7 | 9 | 30:35 | -5 | 34 |
| 20 |
|
Coyotes de Tlaxcala | 24 | 6 | 12 | 6 | 29:27 | 2 | 32 |
| 21 |
|
Reboceros de La Piedad | 24 | 6 | 8 | 10 | 29:35 | -6 | 30 |
| 22 |
|
Albinegros Orizaba | 24 | 8 | 5 | 11 | 19:30 | -11 | 30 |
| 23 |
|
Cocodrilos de Tabasco | 24 | 5 | 10 | 9 | 21:26 | -5 | 28 |
| 24 |
|
Leones Negros II | 24 | 7 | 6 | 11 | 31:39 | -8 | 28 |
| 25 |
|
Tecos Fútbol Club | 24 | 5 | 7 | 12 | 32:40 | -8 | 27 |
| 26 |
|
Pioneros de Cancún | 24 | 4 | 11 | 9 | 23:30 | -7 | 25 |
| 27 |
|
Sporting Canamy | 24 | 6 | 6 | 12 | 26:44 | -18 | 25 |
| 28 |
|
CF América II | 24 | 4 | 10 | 10 | 26:38 | -12 | 24 |
| 29 |
|
Yalmakan FC | 24 | 4 | 9 | 11 | 25:35 | -10 | 23 |
| 30 |
|
Alacranes de Durango | 24 | 4 | 9 | 11 | 19:32 | -13 | 22 |
| 31 |
|
Pacific F. C. | 24 | 3 | 6 | 15 | 23:54 | -31 | 17 |
| 32 |
|
Cimarrones de Sonora II | 24 | 2 | 3 | 19 | 10:66 | -56 | 9 |
| Play-off | |
| Play-off | |
| Play-off | |
| Play-off | |
| Play-off | |
| Play-off | |
| Play-off | |
| Play-off | |
| Play-off | |
| Relégation |
