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| H (Match allé) | Deportivo Guadalajara | - | Atlante | 1:0 (0:0) | ||
| R (match retour) | Atlante | - | Deportivo Guadalajara | 1:0 (1:0) | ||
| H (Match allé): 29.11.2007 04:00 | R (match retour): 02.12.2007 04:00 | |||||
| H (Match allé) | Pumas UNAM | - | Santos Laguna | 3:0 (1:0) | ||
| R (match retour) | Santos Laguna | - | Pumas UNAM | 4:2 (2:1) | ||
| H (Match allé): 30.11.2007 03:00 | R (match retour): 03.12.2007 00:00 | vainqueur: Pumas UNAM | ||||
