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| 06.04.2019 | 16:00 | Puebla FC | - | CD Veracruz | 1:0 (1:0) | |
| 16:00 | Cruz Azul | - | CF América | 1:0 (1:0) | ||
| 16:00 | UANL Tigres | - | Deportivo Guadalajara | 2:1 (1:0) | ||
| 16:00 | Monarcas Morelia | - | Santos Laguna | 1:2 (0:1) | ||
| 16:00 | Atlas Guadalajara | - | Gallos Blancos | 2:0 (1:0) | ||
| 17:00 | Deportivo Toluca | - | Pumas UNAM | 4:2 (1:0) | ||
| 18:00 | Club Tijuana | - | Lobos BUAP | 2:1 (2:1) | ||
| 18:30 | Club León | - | Club Necaxa | 2:0 (1:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Deportivo Guadalajara | 12 | 11 | 0 | 1 | 33:10 | 23 | 33 |
| 2 |
|
Deportivo Toluca | 13 | 10 | 2 | 1 | 29:10 | 19 | 32 |
| 3 |
|
CF Pachuca | 12 | 9 | 3 | 0 | 33:12 | 21 | 30 |
| 4 |
|
Club León | 13 | 9 | 3 | 1 | 22:12 | 10 | 30 |
| 5 |
|
Club Tijuana | 12 | 9 | 2 | 1 | 28:13 | 15 | 29 |
| 6 |
|
Atlas Guadalajara | 12 | 6 | 2 | 4 | 22:17 | 5 | 20 |
| 7 |
|
Club Necaxa | 12 | 6 | 1 | 5 | 15:13 | 2 | 19 |
| 8 |
|
Cruz Azul | 13 | 4 | 5 | 4 | 15:13 | 2 | 17 |
| 9 |
|
Gallos Blancos | 13 | 5 | 2 | 6 | 14:21 | -7 | 17 |
| 10 |
|
CF América | 12 | 5 | 1 | 6 | 15:19 | -4 | 16 |
| 11 |
|
UANL Tigres | 13 | 4 | 3 | 6 | 11:15 | -4 | 15 |
| 12 |
|
Santos Laguna | 13 | 4 | 1 | 8 | 28:28 | 0 | 13 |
| 13 |
|
Puebla FC | 12 | 3 | 4 | 5 | 12:18 | -6 | 13 |
| 14 |
|
Monarcas Morelia | 12 | 3 | 2 | 7 | 10:21 | -11 | 11 |
| 15 |
|
Pumas UNAM | 12 | 2 | 3 | 7 | 11:21 | -10 | 9 |
| 16 |
|
CD Veracruz | 13 | 1 | 3 | 9 | 11:28 | -17 | 6 |
| 17 |
|
Lobos BUAP | 13 | 1 | 1 | 11 | 7:27 | -20 | 4 |
| 18 |
|
CF Monterrey | 12 | 0 | 2 | 10 | 2:20 | -18 | 2 |
