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| H (Match allé) | CF Pachuca | - | Santos Laguna | 1:2 | ||
| R (match retour) | Santos Laguna | - | CF Pachuca | 2:2 | ||
| H (Match allé): 17.05.2018 02:00 | R (match retour): 19.05.2018 17:00 | vainqueur: Santos Laguna | ||||
|
|
|
| H (Match allé) | CF Pachuca | - | Santos Laguna | 1:2 | ||
| R (match retour) | Santos Laguna | - | CF Pachuca | 2:2 | ||
| H (Match allé): 17.05.2018 02:00 | R (match retour): 19.05.2018 17:00 | vainqueur: Santos Laguna | ||||
