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| 27.11.2020 | 18:45 | TOP Oss | - | NAC Breda | 0:0 (0:0) | |
| 18:45 | SC Cambuur | - | FC Den Bosch | 3:1 (1:1) | ||
| 21:00 | FC Volendam | - | Almere City FC | 2:2 (1:1) | ||
| 21:00 | Helmond Sport | - | Jong PSV | 1:0 (1:0) | ||
| 28.11.2020 | 14:00 | Roda JC Kerkrade | - | SBV Excelsior | 3:1 (1:1) | |
| 16:30 | FC Dordrecht | - | Jong Ajax | 3:1 (2:1) | ||
| 29.11.2020 | 12:15 | FC Eindhoven | - | De Graafschap | 3:2 (1:1) | |
| 30.11.2020 | 18:45 | FC Utrecht (J) | - | Telstar | 1:2 (1:1) | |
| 21:00 | NEC Nijmegen | - | MVV | 2:1 (1:1) | ||
| 01.12.2020 | 18:45 | Go Ahead Eagles | - | AZ Alkmaar (J) | 0:1 (0:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SC Cambuur | 14 | 11 | 1 | 2 | 48:14 | 34 | 34 |
| 2 |
|
Almere City FC | 14 | 9 | 4 | 1 | 32:18 | 14 | 31 |
| 3 |
|
NAC Breda | 14 | 9 | 1 | 4 | 27:14 | 13 | 28 |
| 4 |
|
De Graafschap | 14 | 9 | 1 | 4 | 28:22 | 6 | 28 |
| 5 |
|
NEC Nijmegen | 14 | 8 | 3 | 3 | 27:14 | 13 | 27 |
| 6 |
|
FC Volendam | 14 | 6 | 6 | 2 | 34:17 | 17 | 24 |
| 7 |
|
Telstar | 14 | 6 | 4 | 4 | 24:18 | 6 | 22 |
| 8 |
|
FC Eindhoven | 14 | 6 | 3 | 5 | 24:27 | -3 | 21 |
| 9 |
|
SBV Excelsior | 14 | 6 | 2 | 6 | 28:22 | 6 | 20 |
| 10 |
|
Roda JC Kerkrade | 14 | 5 | 5 | 4 | 23:18 | 5 | 20 |
| 11 |
|
Jong Ajax | 14 | 6 | 2 | 6 | 27:29 | -2 | 20 |
| 12 |
|
Go Ahead Eagles | 14 | 5 | 4 | 5 | 15:13 | 2 | 19 |
| 13 |
|
FC Utrecht (J) | 14 | 5 | 1 | 8 | 20:25 | -5 | 16 |
| 14 |
|
Jong PSV | 14 | 4 | 3 | 7 | 21:27 | -6 | 15 |
| 15 |
|
Helmond Sport | 14 | 4 | 3 | 7 | 13:22 | -9 | 15 |
| 16 |
|
TOP Oss | 14 | 3 | 4 | 7 | 10:21 | -11 | 13 |
| 17 |
|
AZ Alkmaar (J) | 14 | 3 | 2 | 9 | 21:41 | -20 | 11 |
| 18 |
|
MVV | 14 | 2 | 4 | 8 | 16:34 | -18 | 10 |
| 19 |
|
FC Den Bosch | 14 | 2 | 3 | 9 | 14:29 | -15 | 9 |
| 20 |
|
FC Dordrecht | 14 | 2 | 2 | 10 | 11:38 | -27 | 8 |
| Promotion | |
| Play-off |
