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| 24.04.2019 | 18:00 | FK Rostov | - | Lokomotiv Moskva | 1:2 (1:1) | |
| 18:00 | Akhmat Grozny | - | FK Krasnodar | 1:1 (1:0) | ||
| 18:30 | Rubin Kazan | - | FK Ufa | 1:1 (0:1) | ||
| 18:30 | CSKA Moskva | - | Anzhi Makhachkala | 2:0 (1:0) | ||
| 20:00 | Zenit St. Petersburg | - | Dinamo Moskva | 2:0 (0:0) | ||
| 25.04.2019 | 15:00 | Enisey Krasnoyarsk | - | FK Orenburg | 2:1 (1:0) | |
| 17:30 | Krylia Sovetov | - | FK Ural | 0:1 (0:0) | ||
| 19:30 | Arsenal Tula | - | Spartak Moskva | 3:0 (3:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Zenit St. Petersburg | 25 | 17 | 3 | 5 | 45:23 | 22 | 54 |
| 2 |
|
Lokomotiv Moskva | 25 | 13 | 7 | 5 | 36:23 | 13 | 46 |
| 3 |
|
CSKA Moskva | 25 | 12 | 8 | 5 | 36:16 | 20 | 44 |
| 4 |
|
FK Krasnodar | 25 | 12 | 7 | 6 | 44:22 | 22 | 43 |
| 5 |
|
Spartak Moskva | 25 | 11 | 6 | 8 | 31:27 | 4 | 39 |
| 6 |
|
Arsenal Tula | 25 | 10 | 8 | 7 | 33:26 | 7 | 38 |
| 7 |
|
FK Orenburg | 25 | 10 | 5 | 10 | 32:29 | 3 | 35 |
| 8 |
|
FK Rostov | 25 | 9 | 8 | 8 | 22:20 | 2 | 35 |
| 9 |
|
Akhmat Grozny | 25 | 9 | 7 | 9 | 24:27 | -3 | 34 |
| 10 |
|
FK Ural | 25 | 9 | 6 | 10 | 26:36 | -10 | 33 |
| 11 |
|
Rubin Kazan | 25 | 6 | 13 | 6 | 21:24 | -3 | 31 |
| 12 |
|
Dinamo Moskva | 25 | 6 | 10 | 9 | 21:21 | 0 | 28 |
| 13 |
|
Krylia Sovetov | 25 | 8 | 3 | 14 | 20:31 | -11 | 27 |
| 14 |
|
FK Ufa | 25 | 4 | 10 | 11 | 19:28 | -9 | 22 |
| 15 |
|
Anzhi Makhachkala | 25 | 5 | 4 | 16 | 11:43 | -32 | 19 |
| 16 |
|
Enisey Krasnoyarsk | 25 | 3 | 7 | 15 | 17:42 | -25 | 16 |
| Champions League | |
| Champions League Quali. | |
| Europa League | |
| Europa League Quali. | |
| Relégation | |
| Relégation |
