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| 10.05.2019 | 10:30 | FK Orenburg | - | FK Ural | 2:2 (0:0) | |
| 13:00 | Dinamo Moskva | - | FK Rostov | 0:0 (0:0) | ||
| 15:30 | Anzhi Makhachkala | - | Arsenal Tula | 0:1 (0:1) | ||
| 18:00 | Lokomotiv Moskva | - | Rubin Kazan | 4:0 (2:0) | ||
| 11.05.2019 | 13:00 | Enisey Krasnoyarsk | - | FK Krasnodar | 0:4 (0:2) | |
| 15:30 | Akhmat Grozny | - | Krylia Sovetov | 2:1 (2:1) | ||
| 12.05.2019 | 15:30 | Spartak Moskva | - | FK Ufa | 1:0 (1:0) | |
| 18:00 | Zenit St. Petersburg | - | CSKA Moskva | 3:1 (1:1) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Zenit St. Petersburg | 28 | 19 | 4 | 5 | 53:27 | 26 | 61 |
| 2 |
|
Lokomotiv Moskva | 28 | 15 | 7 | 6 | 42:26 | 16 | 52 |
| 3 |
|
FK Krasnodar | 28 | 14 | 8 | 6 | 51:23 | 28 | 50 |
| 4 |
|
Spartak Moskva | 28 | 13 | 7 | 8 | 34:28 | 6 | 46 |
| 5 |
|
CSKA Moskva | 28 | 12 | 9 | 7 | 39:23 | 16 | 45 |
| 6 |
|
Arsenal Tula | 28 | 12 | 9 | 7 | 37:27 | 10 | 45 |
| 7 |
|
Akhmat Grozny | 28 | 10 | 9 | 9 | 27:29 | -2 | 39 |
| 8 |
|
FK Rostov | 28 | 9 | 11 | 8 | 24:22 | 2 | 38 |
| 9 |
|
FK Orenburg | 28 | 10 | 7 | 11 | 35:34 | 1 | 37 |
| 10 |
|
Rubin Kazan | 28 | 7 | 14 | 7 | 24:29 | -5 | 35 |
| 11 |
|
FK Ural | 28 | 9 | 7 | 12 | 29:43 | -14 | 34 |
| 12 |
|
Dinamo Moskva | 28 | 6 | 13 | 9 | 23:23 | 0 | 31 |
| 13 |
|
Krylia Sovetov | 28 | 8 | 4 | 16 | 24:38 | -14 | 28 |
| 14 |
|
FK Ufa | 28 | 5 | 11 | 12 | 24:31 | -7 | 26 |
| 15 |
|
Anzhi Makhachkala | 28 | 5 | 5 | 18 | 13:48 | -35 | 20 |
| 16 |
|
Enisey Krasnoyarsk | 28 | 4 | 7 | 17 | 21:49 | -28 | 19 |
| Champions League | |
| Champions League Quali. | |
| Europa League | |
| Europa League Quali. | |
| Relégation | |
| Relégation |
