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| H (Match allé) | Colorado Rapids | - | Los Angeles Galaxy | 1:0 (1:0) | ||
| R (match retour) | Los Angeles Galaxy | - | Colorado Rapids | 2:0 (2:0) | ||
| H (Match allé): 23.10.2004 03:30 | R (match retour): 31.10.2004 03:00 | vainqueur: Los Angeles Galaxy | ||||
| H (Match allé) | New England Revolution | - | Columbus Crew | 1:0 (1:0) | ||
| R (match retour) | Columbus Crew | - | New England Revolution | 1:1 (0:0) | ||
| H (Match allé): 24.10.2004 01:30 | R (match retour): 31.10.2004 23:00 | vainqueur: New England Revolution | ||||
| H (Match allé) | MetroStars | - | D.C. United | 0:2 (0:0) | ||
| R (match retour) | D.C. United | - | MetroStars | 2:0 (0:0) | ||
| H (Match allé): 24.10.2004 01:30 | R (match retour): 31.10.2004 01:00 | vainqueur: D.C. United | ||||
| H (Match allé) | San Jose Earthquakes | - | Kansas City Wizards | 2:0 (1:0) | ||
| R (match retour) | Kansas City Wizards | - | San Jose Earthquakes | 3:0 (1:0) | ||
| H (Match allé): 24.10.2004 23:00 | R (match retour): 31.10.2004 02:30 | vainqueur: Kansas City Wizards | ||||
