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| H (Match allé) | Houston Dynamo | - | D.C. United | 3:1 (0:1) | ||
| R (match retour) | D.C. United | - | Houston Dynamo | 1:1 (0:1) | ||
| H (Match allé): 11.11.2012 22:00 | R (match retour): 18.11.2012 22:00 | vainqueur: Houston Dynamo | ||||
| H (Match allé) | Los Angeles Galaxy | - | Seattle Sounders | 3:0 (0:0) | ||
| R (match retour) | Seattle Sounders | - | Los Angeles Galaxy | 2:1 (1:0) | ||
| H (Match allé): 12.11.2012 03:00 | R (match retour): 19.11.2012 03:00 | vainqueur: Los Angeles Galaxy | ||||
