Under-fire Arsenal manager Arsene Wenger handed 19-year-old Alex Iwobi his first Champions League start as the Gunners face a huge task in overturning a 2-0 deficit in their Champions last 16, second leg at Barcelona.

Wenger makes six changes in all from the first leg at the Emirates Stadium three weeks ago without the injured Petr Cech, Aaron Ramsey and Alex Oxlade-Chamberlain, while Per Mertesacker, Olivier Giroud and Francis Coquelin drop to the bench.

Laurent Koscielny returns in central defence, while Danny Welbeck is supported in attack by Iwobi, Mesut Ozil and Alexis Sanchez on his return to the Camp Nou.

Barca coach Luis Enrique names his strongest available side in the absence of Gerard Pique through suspension.

Jeremy Mathieu replaces the Spanish international in the European champions' only change from the first leg.

Lionel Messi, Luis Suarez and Neymar start up front looking to build on their combined 103 goals already this season.

Starting line-ups

Barcelona (4-3-3)

Marc-Andre ter Stegen; Dani Alves, Jeremy Mathieu, Javier Mascherano, Jordi Alba; Ivan Rakitic, Sergio Busquets, Andres Iniesta (capt); Lionel Messi, Luis Suarez, Neymar

Coach: Luis Enrique (ESP)

Arsenal (4-2-3-1)

David Ospina; Hector Bellerin, Gabriel, Laurent Koscielny (capt), Nacho Monreal; Mathieu Flamini, Mohamed Elneny; Alex Iwobi, Mesut Ozil, Alexis Sanchez; Danny Welbeck

Coach: Arsene Wenger (FRA)

Referee: Sergei Karasev (RUS)