Sampdoria advanced to the last 16 of the Italian Cup on Tuesday as Serie A rivals Cagliari and SPAL both fell to lower league sides.

Cagliari were shocked 2-1 in Sardinia by Serie C side Pordenone, while SPAL lost 2-0 at home to Serie B outfit Cittadella in fourth round action.

Pordenone, from near Venice, take on big-hitters Inter Milan in the last 16 on December 13 while Cittadella, a team from a medieval walled city near Padua, travel down to Rome to play Lazio.

Sampdoria were three goals up within half against Serie B side Pescara with David Kownacki opening after two minutes followed by goals from Gaston Ramirez and Gianluca Caprari.

Pole Kownacki scored his second came on 74 minutes with Libyan midfielder Ahmad Benali pulling one back from Adriatic Coast side Pescara.

Genoa outfit Sampdoria - sitting sixth in Serie A - next travel to Fiorentina for their last 16 tie.