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| 22.12.2020 | 15:00 | Sigma Olomouc | - | FK Jablonec | 1:3 (1:1) | |
| 17:00 | AC Sparta Praha | - | Slovan Liberec | 1:1 (0:1) | ||
| 23.12.2020 | 15:00 | Zbrojovka Brno | - | Baník Ostrava | 0:1 (0:1) | |
| 15:00 | FC Fastav Zlín | - | FK Teplice | 2:3 (1:2) | ||
| 15:00 | FK Mladá Boleslav | - | 1. FC Slovácko | 2:3 (1:1) | ||
| 15:00 | MFK Karviná | - | FK Pardubice | 0:2 (0:1) | ||
| 17:00 | Viktoria Plzeň | - | Slavia Praha | 0:1 (0:1) | ||
| 20.01.2021 | 16:00 | Dynamo České Budějovice | - | 1. FK Příbram | 2:1 (0:1) | |
| 27.01.2021 | 16:00 | Bohemians Praha 1905 | - | SFC Opava | 0:0 (0:0) |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Slavia Praha | 14 | 12 | 2 | 0 | 42:6 | 36 | 38 |
| 2 |
|
AC Sparta Praha | 14 | 10 | 1 | 3 | 32:18 | 14 | 31 |
| 3 |
|
FK Jablonec | 14 | 9 | 2 | 3 | 26:15 | 11 | 29 |
| 4 |
|
1. FC Slovácko | 14 | 7 | 3 | 4 | 25:16 | 9 | 24 |
| 5 |
|
Baník Ostrava | 14 | 7 | 3 | 4 | 20:12 | 8 | 24 |
| 6 |
|
Sigma Olomouc | 14 | 5 | 7 | 2 | 20:15 | 5 | 22 |
| 7 |
|
FK Pardubice | 14 | 6 | 4 | 4 | 15:15 | 0 | 22 |
| 8 |
|
Slovan Liberec | 14 | 6 | 3 | 5 | 20:16 | 4 | 21 |
| 9 |
|
Viktoria Plzeň | 14 | 6 | 2 | 6 | 28:21 | 7 | 20 |
| 10 |
|
MFK Karviná | 14 | 5 | 5 | 4 | 14:18 | -4 | 20 |
| 11 |
|
Dynamo České Budějovice | 14 | 4 | 6 | 4 | 19:23 | -4 | 18 |
| 12 |
|
FC Fastav Zlín | 14 | 5 | 1 | 8 | 17:23 | -6 | 16 |
| 13 |
|
FK Teplice | 14 | 5 | 1 | 8 | 16:28 | -12 | 16 |
| 14 |
|
Bohemians Praha 1905 | 14 | 4 | 3 | 7 | 16:18 | -2 | 15 |
| 15 |
|
FK Mladá Boleslav | 14 | 2 | 3 | 9 | 16:28 | -12 | 9 |
| 16 |
|
Zbrojovka Brno | 14 | 2 | 3 | 9 | 12:27 | -15 | 9 |
| 17 |
|
1. FK Příbram | 14 | 2 | 3 | 9 | 11:30 | -19 | 9 |
| 18 |
|
SFC Opava | 14 | 1 | 4 | 9 | 10:30 | -20 | 7 |
| Champions League Quali. | |
| Europa League Quali. | |
| Relégation |
