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| H (Match allé) | Atlético Choloma | - | Marathón | 0:0 | ||
| R (match retour) | Marathón | - | Atlético Choloma | 2:2 | ||
| H (Match allé): 17.11.2012 01:30 | R (match retour): 22.11.2012 02:30 | vainqueur: Atlético Choloma | ||||
| H (Match allé) | Real España | - | Motagua | 1:4 | ||
| R (match retour) | Motagua | - | Real España | 3:2 | ||
| H (Match allé): 17.11.2012 02:00 | R (match retour): 22.11.2012 02:00 | vainqueur: Motagua | ||||
