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| H (Match allé) | Stal Dniprodzerzhynsk | - | Dnipro Dnipropetrovsk | 0:3 (0:1) | ||
| R (match retour) | Dnipro Dnipropetrovsk | - | Stal Dniprodzerzhynsk | 4:1 (1:0) | ||
| H (Match allé): 01.03.2016 16:00 | R (match retour): 06.04.2016 18:00 | vainqueur: Dnipro Dnipropetrovsk | ||||
| H (Match allé) | FK Oleksandriya | - | Dinamo Kiev | 1:1 (1:0) | ||
| R (match retour) | Dinamo Kiev | - | FK Oleksandriya | 0:1 (0:1) | ||
| H (Match allé): 01.03.2016 18:00 | R (match retour): 06.04.2016 16:00 | vainqueur: FK Oleksandriya | ||||
| H (Match allé) | Volyn Lutsk | - | Zorya Lugansk | 1:1 (1:1) | ||
| R (match retour) | Zorya Lugansk | - | Volyn Lutsk | 5:0 (1:0) | ||
| H (Match allé): 02.03.2016 18:00 | R (match retour): 06.04.2016 13:00 | vainqueur: Zorya Lugansk | ||||
| H (Match allé) | Vorskla Poltava | - | Shakhtar Donetsk | 0:4 (0:1) | ||
| R (match retour) | Shakhtar Donetsk | - | Vorskla Poltava | 1:2 (0:1) | ||
| H (Match allé): 02.03.2016 18:30 | R (match retour): 27.03.2016 16:00 | vainqueur: Shakhtar Donetsk | ||||
