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| H (Match allé) | Butrinti Sarandë | - | KF Skënderbeu | 1:1 | ||
| R (match retour) | KF Skënderbeu | - | Butrinti Sarandë | 8:0 | ||
| H (Match allé): 28.09.2016 16:00 | R (match retour): 05.10.2016 14:00 | vainqueur: KF Skënderbeu | ||||
| H (Match allé) | FK Tomori Berat | - | FK Kukësi | 0:3 | ||
| R (match retour) | FK Kukësi | - | FK Tomori Berat | 1:0 | ||
| H (Match allé): 28.09.2016 16:00 | R (match retour): 05.10.2016 14:00 | vainqueur: FK Kukësi | ||||
| H (Match allé) | Sopoti Librazhd | - | KF Tiranë | 1:1 | ||
| R (match retour) | KF Tiranë | - | Sopoti Librazhd | 7:0 | ||
| H (Match allé): 28.09.2016 16:00 | R (match retour): 05.10.2016 14:00 | vainqueur: KF Tiranë | ||||
| H (Match allé) | Turbina Cërrik | - | KF Laçi | 0:2 | ||
| R (match retour) | KF Laçi | - | Turbina Cërrik | 3:0 | ||
| H (Match allé): 28.09.2016 16:00 | R (match retour): 05.10.2016 14:00 | vainqueur: KF Laçi | ||||
| H (Match allé) | KS Shkumbini | - | KF Bylis Ballsh | 1:3 | ||
| R (match retour) | KF Bylis Ballsh | - | KS Shkumbini | 4:0 | ||
| H (Match allé): 28.09.2016 16:00 | R (match retour): 05.10.2016 14:00 | vainqueur: KF Bylis Ballsh | ||||
| H (Match allé) | KF Elbasani | - | Luftëtari Gjirokastër | 0:1 | ||
| R (match retour) | Luftëtari Gjirokastër | - | KF Elbasani | 2:2 | ||
| H (Match allé): 28.09.2016 16:00 | R (match retour): 05.10.2016 14:00 | vainqueur: Luftëtari Gjirokastër | ||||
| H (Match allé) | Dinamo Tiranë | - | KS Pogradeci | 2:1 | ||
| R (match retour) | KS Pogradeci | - | Dinamo Tiranë | 1:1 | ||
| H (Match allé): 28.09.2016 16:00 | R (match retour): 05.10.2016 14:00 | vainqueur: Dinamo Tiranë | ||||
| H (Match allé) | KF Lushnja | - | KF Apolonia Fier | 1:3 | ||
| R (match retour) | KF Apolonia Fier | - | KF Lushnja | 1:0 | ||
| H (Match allé): 28.09.2016 16:00 | R (match retour): 05.10.2016 14:00 | vainqueur: KF Apolonia Fier | ||||
| H (Match allé) | FC Kevitan | - | FK Partizani | 1:5 | ||
| R (match retour) | FK Partizani | - | FC Kevitan | 4:0 | ||
| H (Match allé): 28.09.2016 16:00 | R (match retour): 06.10.2016 14:00 | vainqueur: FK Partizani | ||||
| H (Match allé) | FK Shënkolli | - | KF Teuta Durrës | 0:0 | ||
| R (match retour) | KF Teuta Durrës | - | FK Shënkolli | 2:0 | ||
| H (Match allé): 28.09.2016 16:00 | R (match retour): 05.10.2016 14:00 | vainqueur: KF Teuta Durrës | ||||
| H (Match allé) | KF Adriatiku Mamurrasi | - | FK Vllaznia | 0:3 | ||
| R (match retour) | FK Vllaznia | - | KF Adriatiku Mamurrasi | 4:0 | ||
| H (Match allé): 28.09.2016 16:00 | R (match retour): 05.10.2016 14:00 | vainqueur: FK Vllaznia | ||||
| H (Match allé) | KS Iliria | - | Flamurtari Vlorë | 1:0 | ||
| R (match retour) | Flamurtari Vlorë | - | KS Iliria | 6:0 | ||
| H (Match allé): 28.09.2016 16:00 | R (match retour): 05.10.2016 14:00 | vainqueur: Flamurtari Vlorë | ||||
| H (Match allé) | KS Besa | - | KF Tërbuni Pukë | 1:1 | ||
| R (match retour) | KF Tërbuni Pukë | - | KS Besa | 4:1 | ||
| H (Match allé): 28.09.2016 16:00 | R (match retour): 05.10.2016 14:00 | vainqueur: KF Tërbuni Pukë | ||||
| H (Match allé) | KS Kamza | - | KS Korabi Peshkopi | 1:1 | ||
| R (match retour) | KS Korabi Peshkopi | - | KS Kamza | 0:2 | ||
| H (Match allé): 28.09.2016 16:00 | R (match retour): 05.10.2016 14:00 | vainqueur: KS Kamza | ||||
| H (Match allé) | KS Burreli | - | KS Kastrioti | 3:1 | ||
| R (match retour) | KS Kastrioti | - | KS Burreli | 4:1 | ||
| H (Match allé): 28.09.2016 16:00 | R (match retour): 05.10.2016 14:00 | vainqueur: KS Kastrioti | ||||
| H (Match allé) | Erzeni Shijak | - | KS Besëlidhja Lezhë | 1:3 | ||
| R (match retour) | KS Besëlidhja Lezhë | - | Erzeni Shijak | 2:2 | ||
| H (Match allé): 28.09.2016 16:00 | R (match retour): 05.10.2016 14:00 | vainqueur: KS Besëlidhja Lezhë | ||||
