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| 29.10.2018 | 19:30 | KAS Eupen II | - | KRC Genk II | 1:0 | |
| 19:30 | Sint-Truidense VV II | - | Club Brugge KV II | 2:1 | ||
| 19:30 | RSC Anderlecht II | - | Sporting Lokeren II | 1:1 | ||
| 19:30 | SK Beveren II | - | Sporting Charleroi II | 0:1 | ||
| 19:30 | Standard Liège II | - | Royal Excel Mouscron II | 3:0 | ||
| 19:30 | KAA Gent II | - | SV Zulte Waregem II | 2:1 | ||
| 20:00 | KV Kortrijk II | - | Royal Antwerp FC II | 3:1 | ||
| 20:00 | Cercle Brugge II | - | KV Oostende II | 4:1 |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Royal Antwerp FC II | 10 | 7 | 1 | 2 | 26:12 | 14 | 22 |
| 2 |
|
KRC Genk II | 10 | 7 | 0 | 3 | 21:9 | 12 | 21 |
| 3 |
|
RSC Anderlecht II | 10 | 6 | 1 | 3 | 27:17 | 10 | 19 |
| 4 |
|
KAS Eupen II | 10 | 6 | 1 | 3 | 23:14 | 9 | 19 |
| 5 |
|
Club Brugge KV II | 10 | 6 | 1 | 3 | 16:13 | 3 | 19 |
| 6 |
|
KAA Gent II | 10 | 5 | 2 | 3 | 18:16 | 2 | 17 |
| 7 |
|
Sint-Truidense VV II | 10 | 5 | 1 | 4 | 22:20 | 2 | 16 |
| 8 |
|
Standard Liège II | 10 | 5 | 1 | 4 | 16:16 | 0 | 16 |
| 9 |
|
Sporting Lokeren II | 10 | 4 | 3 | 3 | 14:16 | -2 | 15 |
| 10 |
|
Cercle Brugge II | 10 | 4 | 1 | 5 | 16:18 | -2 | 13 |
| 11 |
|
KV Kortrijk II | 10 | 4 | 1 | 5 | 14:18 | -4 | 13 |
| 12 |
|
Sporting Charleroi II | 10 | 3 | 2 | 5 | 13:13 | 0 | 11 |
| 13 |
|
KV Oostende II | 10 | 3 | 1 | 6 | 15:20 | -5 | 10 |
| 14 |
|
SK Beveren II | 10 | 3 | 0 | 7 | 9:20 | -11 | 9 |
| 15 |
|
Royal Excel Mouscron II | 10 | 1 | 2 | 7 | 6:21 | -15 | 5 |
| 16 |
|
SV Zulte Waregem II | 10 | 1 | 2 | 7 | 12:25 | -13 | 5 |
| Play-off | |
| Relégation |
