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| 07.05.2022 | 01:30 | Royal Pari | - | CD Guabirá | 1:3 (1:0) | |
| 21:00 | Real Tomayapo | - | Nacional Potosí | 1:0 (0:0) | ||
| 23:15 | Universitario de Vinto | - | Atlético Palmaflor | 0:1 (0:0) | ||
| 08.05.2022 | 01:00 | Independiente Petrolero | - | Universitario de Sucre | 1:0 (0:0) | |
| 21:00 | Bolívar | - | The Strongest | 1:0 (1:0) | ||
| 21:00 | Always Ready | - | Real Santa Cruz | 5:0 (0:0) | ||
| 23:15 | Jorge Wilstermann | - | Club Aurora | 0:0 (0:0) | ||
| 09.05.2022 | 01:30 | Blooming | - | Oriente Petrolero | 1:2 (1:2) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| 1 | |||||||||
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
The Strongest | 13 | 6 | 4 | 3 | 19:10 | 9 | 22 |
| 2 |
|
Atlético Palmaflor | 13 | 7 | 1 | 5 | 13:16 | -3 | 22 |
| 3 |
|
Oriente Petrolero | 13 | 6 | 3 | 4 | 18:15 | 3 | 21 |
| 4 |
|
Nacional Potosí | 13 | 5 | 3 | 5 | 23:19 | 4 | 18 |
| 5 |
|
Club Aurora | 13 | 4 | 5 | 4 | 14:13 | 1 | 17 |
| 6 |
|
Universitario de Sucre | 13 | 4 | 3 | 6 | 15:17 | -2 | 15 |
| 7 |
|
Real Santa Cruz | 13 | 3 | 3 | 7 | 15:23 | -8 | 12 |
| 8 |
|
CD Guabirá | 13 | 3 | 3 | 7 | 13:21 | -8 | 12 |
| 2 | |||||||||
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Bolívar | 13 | 10 | 1 | 2 | 36:6 | 30 | 31 |
| 2 |
|
Blooming | 13 | 6 | 3 | 4 | 21:26 | -5 | 21 |
| 3 |
|
Royal Pari | 13 | 5 | 4 | 4 | 28:22 | 6 | 19 |
| 4 |
|
Real Tomayapo | 13 | 4 | 5 | 4 | 12:20 | -8 | 17 |
| 5 |
|
Always Ready | 13 | 4 | 4 | 5 | 20:19 | 1 | 16 |
| 6 |
|
Independiente Petrolero | 13 | 4 | 4 | 5 | 17:22 | -5 | 16 |
| 7 |
|
Jorge Wilstermann | 13 | 3 | 5 | 5 | 13:15 | -2 | 14 |
| 8 |
|
Universitario de Vinto | 13 | 3 | 3 | 7 | 13:26 | -13 | 12 |
| Play-off | |
| Play-off |
