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| 08.04.2022 | 21:00 | Always Ready | - | Universitario de Vinto | 6:2 (2:1) | |
| 09.04.2022 | 21:00 | Atlético Palmaflor | - | Real Santa Cruz | 2:1 (0:1) | |
| 21:00 | Royal Pari | - | Independiente Petrolero | 5:1 (0:0) | ||
| 23:15 | Bolívar | - | Jorge Wilstermann | 0:1 (0:1) | ||
| 10.04.2022 | 01:30 | Oriente Petrolero | - | Nacional Potosí | 4:2 (1:0) | |
| 21:00 | Universitario de Sucre | - | CD Guabirá | 2:0 (1:0) | ||
| 23:15 | Real Tomayapo | - | Blooming | 1:2 (1:1) | ||
| 12.04.2022 | 00:30 | Club Aurora | - | The Strongest | 1:0 (0:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| 1 | |||||||||
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Atlético Palmaflor | 8 | 5 | 1 | 2 | 9:9 | 0 | 16 |
| 2 |
|
Nacional Potosí | 8 | 4 | 2 | 2 | 18:12 | 6 | 14 |
| 3 |
|
The Strongest | 8 | 4 | 2 | 2 | 12:6 | 6 | 14 |
| 4 |
|
Universitario de Sucre | 8 | 4 | 2 | 2 | 12:8 | 4 | 14 |
| 5 |
|
Oriente Petrolero | 8 | 4 | 0 | 4 | 12:11 | 1 | 12 |
| 6 |
|
Club Aurora | 8 | 2 | 3 | 3 | 7:9 | -2 | 9 |
| 7 |
|
Real Santa Cruz | 8 | 1 | 2 | 5 | 8:12 | -4 | 5 |
| 8 |
|
CD Guabirá | 8 | 0 | 2 | 6 | 5:16 | -11 | 2 |
| 2 | |||||||||
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Blooming | 8 | 6 | 1 | 1 | 15:12 | 3 | 19 |
| 2 |
|
Bolívar | 8 | 5 | 1 | 2 | 20:3 | 17 | 16 |
| 3 |
|
Real Tomayapo | 8 | 3 | 3 | 2 | 8:11 | -3 | 12 |
| 4 |
|
Always Ready | 8 | 3 | 2 | 3 | 11:10 | 1 | 11 |
| 5 |
|
Royal Pari | 8 | 3 | 2 | 3 | 13:14 | -1 | 11 |
| 6 |
|
Jorge Wilstermann | 8 | 3 | 1 | 4 | 5:6 | -1 | 10 |
| 7 |
|
Independiente Petrolero | 8 | 2 | 2 | 4 | 10:15 | -5 | 8 |
| 8 |
|
Universitario de Vinto | 8 | 1 | 2 | 5 | 8:19 | -11 | 5 |
| Play-off | |
| Play-off |
