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| H (Match allé) | Deportivo Guastatoya | - | Xelaju MC | 1:1 (0:1) | ||
| R (match retour) | Xelaju MC | - | Deportivo Guastatoya | 0:2 (0:1) | ||
| H (Match allé): 28.01.2021 18:00 | R (match retour): 31.01.2021 22:00 | vainqueur: Deportivo Guastatoya | ||||
| H (Match allé) | Antigua GFC | - | CSD Municipal | 1:1 (1:0) | ||
| R (match retour) | CSD Municipal | - | Antigua GFC | 1:1 (0:1) | ||
| H (Match allé): 28.01.2021 20:15 | R (match retour): 31.01.2021 18:00 | |||||
