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| H (Match allé) | Platense | - | Motagua | 0:0 | ||
| R (match retour) | Motagua | - | Platense | 3:0 | ||
| H (Match allé): 01.05.2019 23:00 | R (match retour): 06.05.2019 00:00 | vainqueur: Motagua | ||||
| H (Match allé) | Lobos UPNFM | - | Real España | 3:1 | ||
| R (match retour) | Real España | - | Lobos UPNFM | 1:2 | ||
| H (Match allé): 02.05.2019 00:00 | R (match retour): 06.05.2019 02:00 | vainqueur: Lobos UPNFM | ||||
