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| 26.02.2022 | 14:30 | AFC Ajax Zaterdag | - | SteDoCo | 3:1 (1:0) | |
| 14:30 | Excelsior '31 | - | HSV Hoek | 0:0 (0:0) | ||
| 14:30 | Harkemase Boys | - | VVOG Harderwijk | 1:1 (0:1) | ||
| 14:30 | VV GOES | - | VV DOVO Veenendaal | 2:0 (1:0) | ||
| 14:30 | ACV Assen | - | ODIN '59 | 0:1 (0:0) | ||
| 15:00 | Sparta Nijkerk | - | FC Lisse | 2:1 (0:0) | ||
| 15:00 | Ter Leede | - | DVS'33 | 3:1 (1:1) | ||
| 15:30 | VV Sint Bavo | - | BVV Barendrecht | 0:1 (0:1) | ||
| 15.03.2022 | 20:00 | Sportlust '46 | - | VV Staphorst | 4:2 (3:1) |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Sparta Nijkerk | 16 | 10 | 3 | 3 | 30:17 | 13 | 33 |
| 2 |
|
FC Lisse | 16 | 10 | 2 | 4 | 34:19 | 15 | 32 |
| 3 |
|
Sportlust '46 | 16 | 10 | 2 | 4 | 36:23 | 13 | 32 |
| 4 |
|
Excelsior '31 | 16 | 8 | 3 | 5 | 30:22 | 8 | 27 |
| 5 |
|
BVV Barendrecht | 16 | 6 | 6 | 4 | 31:26 | 5 | 24 |
| 6 |
|
Ter Leede | 16 | 7 | 3 | 6 | 22:26 | -4 | 24 |
| 7 |
|
Harkemase Boys | 16 | 6 | 5 | 5 | 33:29 | 4 | 23 |
| 8 |
|
SteDoCo | 16 | 6 | 4 | 6 | 26:23 | 3 | 22 |
| 9 |
|
HSV Hoek | 16 | 6 | 4 | 6 | 24:21 | 3 | 22 |
| 10 |
|
VV Staphorst | 16 | 6 | 4 | 6 | 23:25 | -2 | 22 |
| 11 |
|
DVS'33 | 16 | 6 | 3 | 7 | 22:21 | 1 | 21 |
| 12 |
|
ODIN '59 | 16 | 6 | 3 | 7 | 24:30 | -6 | 21 |
| 13 |
|
AFC Ajax Zaterdag | 16 | 6 | 3 | 7 | 21:29 | -8 | 21 |
| 14 |
|
ACV Assen | 16 | 5 | 3 | 8 | 19:22 | -3 | 18 |
| 15 |
|
VV DOVO Veenendaal | 16 | 4 | 4 | 8 | 17:25 | -8 | 16 |
| 16 |
|
VVOG Harderwijk | 16 | 3 | 6 | 7 | 28:39 | -11 | 15 |
| 17 |
|
VV Sint Bavo | 16 | 3 | 4 | 9 | 18:29 | -11 | 13 |
| 18 |
|
VV GOES | 16 | 2 | 6 | 8 | 22:34 | -12 | 12 |
| Promotion | |
| Relégation | |
| Relégation |
