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| 19.09.2021 | 14:00 | USV Hercules | - | VV UNA | 4:1 (1:0) | |
| 14:00 | VV Hoogland | - | EVV | 0:0 (0:0) | ||
| 14:00 | VV Dongen | - | HSC'21 | 1:1 (0:0) | ||
| 14:00 | HVV Hollandia | - | OFC Oostzaan | 1:1 (1:0) | ||
| 14:00 | Quick Den Haag | - | JOS Watergraafsmeer | 1:0 (0:0) | ||
| 14:00 | Blauw Geel '38 | - | ADO '20 | 0:2 (0:1) | ||
| 14:00 | RKVV DEM | - | VV Gemert | 1:2 (0:1) | ||
| 14:00 | Unitas Gorinchem | - | OSS '20 | 4:2 (2:1) | ||
| 14:30 | RKSV Groene Ster | - | RKVV Westlandia | 0:0 (0:0) |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
OFC Oostzaan | 5 | 4 | 1 | 0 | 9:4 | 5 | 13 |
| 2 |
|
VV Gemert | 5 | 3 | 2 | 0 | 12:7 | 5 | 11 |
| 3 |
|
USV Hercules | 5 | 3 | 1 | 1 | 12:5 | 7 | 10 |
| 4 |
|
Unitas Gorinchem | 5 | 3 | 1 | 1 | 9:5 | 4 | 10 |
| 5 |
|
VV UNA | 5 | 3 | 0 | 2 | 10:9 | 1 | 9 |
| 6 |
|
RKVV Westlandia | 5 | 2 | 2 | 1 | 8:3 | 5 | 8 |
| 7 |
|
OSS '20 | 5 | 3 | 0 | 2 | 11:8 | 3 | 8 |
| 8 |
|
RKSV Groene Ster | 5 | 2 | 2 | 1 | 10:9 | 1 | 8 |
| 9 |
|
Quick Den Haag | 5 | 2 | 1 | 2 | 3:3 | 0 | 7 |
| 10 |
|
ADO '20 | 5 | 2 | 0 | 3 | 9:10 | -1 | 6 |
| 11 |
|
EVV | 5 | 1 | 3 | 1 | 4:5 | -1 | 6 |
| 12 |
|
Blauw Geel '38 | 5 | 2 | 0 | 3 | 6:10 | -4 | 6 |
| 13 |
|
JOS Watergraafsmeer | 5 | 2 | 1 | 2 | 8:7 | 1 | 5 |
| 14 |
|
VV Dongen | 5 | 1 | 2 | 2 | 7:6 | 1 | 5 |
| 15 |
|
VV Hoogland | 5 | 0 | 3 | 2 | 3:9 | -6 | 3 |
| 16 |
|
HVV Hollandia | 5 | 0 | 2 | 3 | 1:7 | -6 | 2 |
| 17 |
|
RKVV DEM | 5 | 0 | 2 | 3 | 2:9 | -7 | 2 |
| 18 |
|
HSC'21 | 5 | 0 | 1 | 4 | 4:12 | -8 | 1 |
| Promotion | |
| Relégation | |
| Relégation |
