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| 19.01.2018 | 20:00 | FC Dordrecht | - | Fortuna Sittard | 3:0 (1:0) | |
| 20:00 | Go Ahead Eagles | - | MVV | 3:1 (2:0) | ||
| 20:00 | De Graafschap | - | Jong PSV | 2:3 (2:1) | ||
| 20:00 | FC Oss | - | FC Utrecht (J) | 2:0 (0:0) | ||
| 20:00 | Almere City FC | - | NEC Nijmegen | 3:2 (2:0) | ||
| 20:00 | Telstar | - | FC Eindhoven | 4:1 (3:1) | ||
| 20:00 | Helmond Sport | - | FC Volendam | 1:4 (0:3) | ||
| 20:00 | FC Emmen | - | RKC Waalwijk | 2:1 (2:1) | ||
| 22.01.2018 | 20:00 | Jong Ajax | - | SC Cambuur | 3:2 (3:0) | |
| 20:00 | AZ Alkmaar (J) | - | FC Den Bosch | 1:1 (1:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Fortuna Sittard | 21 | 14 | 2 | 5 | 53:26 | 27 | 44 |
| 2 |
|
NEC Nijmegen | 21 | 13 | 4 | 4 | 54:29 | 25 | 43 |
| 3 |
|
Jong Ajax | 21 | 13 | 3 | 5 | 51:30 | 21 | 42 |
| 4 |
|
Telstar | 21 | 10 | 7 | 4 | 40:38 | 2 | 37 |
| 5 |
|
Jong PSV | 21 | 10 | 4 | 7 | 39:35 | 4 | 34 |
| 6 |
|
Almere City FC | 21 | 9 | 6 | 6 | 42:39 | 3 | 33 |
| 7 |
|
FC Oss | 21 | 9 | 6 | 6 | 32:33 | -1 | 33 |
| 8 |
|
FC Emmen | 21 | 7 | 11 | 3 | 32:26 | 6 | 32 |
| 9 |
|
De Graafschap | 21 | 7 | 8 | 6 | 37:25 | 12 | 29 |
| 10 |
|
FC Den Bosch | 21 | 7 | 8 | 6 | 36:29 | 7 | 29 |
| 11 |
|
FC Eindhoven | 21 | 8 | 4 | 9 | 31:41 | -10 | 28 |
| 12 |
|
MVV | 21 | 7 | 5 | 9 | 31:33 | -2 | 26 |
| 13 |
|
SC Cambuur | 21 | 7 | 5 | 9 | 27:32 | -5 | 26 |
| 14 |
|
FC Dordrecht | 21 | 7 | 4 | 10 | 31:47 | -16 | 25 |
| 15 |
|
Go Ahead Eagles | 21 | 5 | 8 | 8 | 31:36 | -5 | 23 |
| 16 |
|
FC Volendam | 21 | 6 | 5 | 10 | 28:35 | -7 | 23 |
| 17 |
|
RKC Waalwijk | 21 | 5 | 7 | 9 | 21:31 | -10 | 22 |
| 18 |
|
Helmond Sport | 21 | 4 | 7 | 10 | 25:35 | -10 | 19 |
| 19 |
|
AZ Alkmaar (J) | 21 | 5 | 2 | 14 | 27:45 | -18 | 17 |
| 20 |
|
FC Utrecht (J) | 21 | 2 | 4 | 15 | 17:40 | -23 | 10 |
| Promotion | |
| Play-off | |
| Play-off | |
| Play-off |
