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| 02.04.2018 | 14:30 | SC Cambuur | - | FC Eindhoven | 3:2 (0:1) | |
| 14:30 | FC Utrecht (J) | - | Go Ahead Eagles | 1:0 (0:0) | ||
| 14:30 | FC Volendam | - | AZ Alkmaar (J) | 4:1 (1:1) | ||
| 14:30 | FC Dordrecht | - | Jong Ajax | 2:3 (1:2) | ||
| 14:30 | RKC Waalwijk | - | Almere City FC | 0:4 (0:2) | ||
| 14:30 | Jong PSV | - | FC Oss | 5:1 (2:1) | ||
| 14:30 | MVV | - | FC Emmen | 0:1 (0:1) | ||
| 14:30 | Fortuna Sittard | - | Helmond Sport | 3:0 (2:0) | ||
| 14:30 | De Graafschap | - | FC Den Bosch | 2:1 (2:1) | ||
| 14:30 | NEC Nijmegen | - | Telstar | 3:0 (2:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Fortuna Sittard | 33 | 20 | 5 | 8 | 75:40 | 35 | 65 |
| 2 |
|
NEC Nijmegen | 33 | 19 | 7 | 7 | 73:40 | 33 | 64 |
| 3 |
|
Jong Ajax | 33 | 20 | 4 | 9 | 76:48 | 28 | 64 |
| 4 |
|
Jong PSV | 33 | 17 | 6 | 10 | 65:49 | 16 | 57 |
| 5 |
|
FC Emmen | 33 | 13 | 15 | 5 | 50:40 | 10 | 54 |
| 6 |
|
Telstar | 33 | 14 | 12 | 7 | 62:59 | 3 | 54 |
| 7 |
|
De Graafschap | 33 | 14 | 10 | 9 | 63:40 | 23 | 52 |
| 8 |
|
FC Dordrecht | 33 | 14 | 4 | 15 | 51:67 | -16 | 46 |
| 9 |
|
FC Den Bosch | 33 | 11 | 11 | 11 | 53:43 | 10 | 44 |
| 10 |
|
MVV | 33 | 12 | 7 | 14 | 50:48 | 2 | 43 |
| 11 |
|
FC Volendam | 33 | 12 | 7 | 14 | 54:58 | -4 | 43 |
| 12 |
|
SC Cambuur | 33 | 11 | 10 | 12 | 45:49 | -4 | 43 |
| 13 |
|
Almere City FC | 33 | 12 | 7 | 14 | 60:67 | -7 | 43 |
| 14 |
|
FC Oss | 33 | 11 | 8 | 14 | 46:56 | -10 | 41 |
| 15 |
|
AZ Alkmaar (J) | 33 | 12 | 3 | 18 | 47:61 | -14 | 39 |
| 16 |
|
Go Ahead Eagles | 33 | 9 | 10 | 14 | 45:54 | -9 | 37 |
| 17 |
|
FC Eindhoven | 33 | 11 | 4 | 18 | 49:73 | -24 | 37 |
| 18 |
|
Helmond Sport | 33 | 9 | 8 | 16 | 42:53 | -11 | 35 |
| 19 |
|
RKC Waalwijk | 33 | 6 | 11 | 16 | 30:54 | -24 | 29 |
| 20 |
|
FC Utrecht (J) | 33 | 6 | 5 | 22 | 34:71 | -37 | 23 |
| Promotion | |
| Play-off | |
| Play-off | |
| Play-off |
