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| 09.11.2007 | 20:00 | BV Veendam | - | Stormvogels Telstar | 2:0 (1:0) | |
| 20:00 | HFC Haarlem | - | RKC Waalwijk | 2:2 (1:0) | ||
| 20:00 | FC Volendam | - | FC Emmen | 5:1 (1:0) | ||
| 20:00 | Helmond Sport | - | FC Omniworld | 2:1 (1:1) | ||
| 20:00 | MVV | - | Go Ahead Eagles | 0:1 (0:1) | ||
| 20:00 | FC Zwolle | - | SC Cambuur | 4:1 (4:0) | ||
| 20:00 | AGOVV | - | TOP Oss | 1:4 (1:1) | ||
| 20:00 | Fortuna Sittard | - | FC Dordrecht | 2:5 (0:3) | ||
| 20:00 | RBC Roosendaal | - | FC Eindhoven | 3:0 (0:0) | ||
| 11.11.2007 | 14:30 | FC Den Bosch | - | ADO Den Haag | 0:2 (0:1) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
RKC Waalwijk | 16 | 10 | 5 | 1 | 40:21 | 19 | 35 |
| 2 |
|
Go Ahead Eagles | 16 | 11 | 0 | 5 | 31:19 | 12 | 33 |
| 3 |
|
FC Zwolle | 16 | 8 | 5 | 3 | 32:19 | 13 | 29 |
| 4 |
|
FC Den Bosch | 16 | 9 | 2 | 5 | 26:22 | 4 | 29 |
| 5 |
|
FC Volendam | 16 | 8 | 4 | 4 | 37:22 | 15 | 28 |
| 6 |
|
MVV | 16 | 8 | 4 | 4 | 22:17 | 5 | 28 |
| 7 |
|
ADO Den Haag | 16 | 7 | 5 | 4 | 24:20 | 4 | 26 |
| 8 |
|
FC Dordrecht | 16 | 7 | 3 | 6 | 32:22 | 10 | 24 |
| 9 |
|
BV Veendam | 16 | 7 | 5 | 4 | 29:24 | 5 | 23 |
| 10 |
|
RBC Roosendaal | 16 | 6 | 4 | 6 | 23:20 | 3 | 22 |
| 11 |
|
Helmond Sport | 16 | 6 | 4 | 6 | 19:21 | -2 | 22 |
| 12 |
|
TOP Oss | 16 | 5 | 5 | 6 | 22:27 | -5 | 20 |
| 13 |
|
AGOVV | 16 | 7 | 1 | 8 | 27:45 | -18 | 19 |
| 14 |
|
FC Emmen | 16 | 4 | 6 | 6 | 20:30 | -10 | 18 |
| 15 |
|
Fortuna Sittard | 16 | 4 | 4 | 8 | 21:27 | -6 | 16 |
| 16 |
|
SC Cambuur | 16 | 4 | 4 | 8 | 22:32 | -10 | 16 |
| 17 |
|
FC Eindhoven | 16 | 3 | 4 | 9 | 23:38 | -15 | 13 |
| 18 |
|
FC Omniworld | 16 | 2 | 6 | 8 | 24:27 | -3 | 12 |
| 19 |
|
HFC Haarlem | 16 | 2 | 6 | 8 | 16:24 | -8 | 12 |
| 20 |
|
Stormvogels Telstar | 16 | 3 | 1 | 12 | 12:25 | -13 | 10 |
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