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| 14.12.2007 | 20:00 | SC Cambuur | - | Stormvogels Telstar | 0:1 (0:1) | |
| 20:00 | FC Emmen | - | RKC Waalwijk | 1:2 (1:1) | ||
| 20:00 | HFC Haarlem | - | BV Veendam | 3:1 (1:0) | ||
| 20:00 | FC Volendam | - | Helmond Sport | 4:0 (3:0) | ||
| 20:00 | FC Dordrecht | - | Go Ahead Eagles | 5:0 (1:0) | ||
| 20:00 | MVV | - | AGOVV | 2:3 (0:2) | ||
| 20:00 | RBC Roosendaal | - | FC Omniworld | 2:1 (2:1) | ||
| 20:00 | TOP Oss | - | Fortuna Sittard | 2:0 (0:0) | ||
| 15.12.2007 | 19:30 | FC Eindhoven | - | FC Den Bosch | 1:0 (0:0) | |
| 16.12.2007 | 12:30 | FC Zwolle | - | ADO Den Haag | 2:1 (1:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
RKC Waalwijk | 21 | 11 | 8 | 2 | 47:28 | 19 | 41 |
| 2 |
|
FC Zwolle | 21 | 11 | 6 | 4 | 42:25 | 17 | 39 |
| 3 |
|
MVV | 21 | 11 | 5 | 5 | 35:24 | 11 | 38 |
| 4 |
|
FC Den Bosch | 21 | 12 | 2 | 7 | 37:28 | 9 | 38 |
| 5 |
|
Go Ahead Eagles | 21 | 12 | 0 | 9 | 36:32 | 4 | 36 |
| 6 |
|
FC Volendam | 21 | 9 | 8 | 4 | 47:28 | 19 | 35 |
| 7 |
|
FC Dordrecht | 21 | 8 | 6 | 7 | 42:28 | 14 | 30 |
| 8 |
|
RBC Roosendaal | 21 | 8 | 6 | 7 | 31:26 | 5 | 30 |
| 9 |
|
ADO Den Haag | 21 | 8 | 6 | 7 | 31:32 | -1 | 30 |
| 10 |
|
Helmond Sport | 21 | 8 | 5 | 8 | 26:29 | -3 | 29 |
| 11 |
|
TOP Oss | 21 | 7 | 7 | 7 | 31:35 | -4 | 28 |
| 12 |
|
BV Veendam | 21 | 7 | 7 | 7 | 34:36 | -2 | 25 |
| 13 |
|
Stormvogels Telstar | 21 | 8 | 1 | 12 | 22:27 | -5 | 25 |
| 14 |
|
FC Emmen | 21 | 6 | 7 | 8 | 30:41 | -11 | 25 |
| 15 |
|
AGOVV | 21 | 8 | 3 | 10 | 33:53 | -20 | 24 |
| 16 |
|
FC Eindhoven | 21 | 6 | 4 | 11 | 29:45 | -16 | 22 |
| 17 |
|
HFC Haarlem | 21 | 4 | 8 | 9 | 25:32 | -7 | 20 |
| 18 |
|
SC Cambuur | 21 | 5 | 5 | 11 | 27:41 | -14 | 20 |
| 19 |
|
FC Omniworld | 21 | 3 | 9 | 9 | 33:33 | 0 | 18 |
| 20 |
|
Fortuna Sittard | 21 | 4 | 5 | 12 | 22:37 | -15 | 17 |
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