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| 10.03.2008 | 20:00 | BV Veendam | - | FC Den Bosch | 0:3 (0:1) | |
| 20:00 | SC Cambuur | - | FC Emmen | 0:1 (0:0) | ||
| 20:00 | Stormvogels Telstar | - | RKC Waalwijk | 2:0 (0:0) | ||
| 20:00 | MVV | - | Helmond Sport | 0:1 (0:0) | ||
| 20:00 | FC Zwolle | - | Fortuna Sittard | 2:3 (1:1) | ||
| 20:00 | FC Eindhoven | - | ADO Den Haag | 0:0 (0:0) | ||
| 20:00 | AGOVV | - | FC Dordrecht | 3:2 (2:1) | ||
| 20:00 | RBC Roosendaal | - | FC Volendam | 1:2 (1:1) | ||
| 20:00 | TOP Oss | - | Go Ahead Eagles | 1:0 (0:0) | ||
| 20:00 | FC Omniworld | - | HFC Haarlem | 2:0 (1:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
RKC Waalwijk | 32 | 17 | 10 | 5 | 72:40 | 32 | 61 |
| 2 |
|
FC Volendam | 32 | 16 | 11 | 5 | 73:42 | 31 | 59 |
| 3 |
|
FC Zwolle | 32 | 16 | 11 | 5 | 65:37 | 28 | 59 |
| 4 |
|
FC Den Bosch | 32 | 17 | 6 | 9 | 52:36 | 16 | 57 |
| 5 |
|
ADO Den Haag | 32 | 14 | 9 | 9 | 51:42 | 9 | 51 |
| 6 |
|
Helmond Sport | 32 | 15 | 5 | 12 | 46:41 | 5 | 50 |
| 7 |
|
MVV | 32 | 13 | 9 | 10 | 47:45 | 2 | 48 |
| 8 |
|
Go Ahead Eagles | 32 | 14 | 2 | 16 | 50:55 | -5 | 44 |
| 9 |
|
RBC Roosendaal | 32 | 11 | 10 | 11 | 40:40 | 0 | 43 |
| 10 |
|
Stormvogels Telstar | 32 | 13 | 4 | 15 | 38:42 | -4 | 43 |
| 11 |
|
TOP Oss | 32 | 11 | 10 | 11 | 47:54 | -7 | 43 |
| 12 |
|
FC Emmen | 32 | 11 | 10 | 11 | 51:62 | -11 | 43 |
| 13 |
|
FC Dordrecht | 32 | 9 | 11 | 12 | 55:47 | 8 | 38 |
| 14 |
|
FC Omniworld | 32 | 8 | 13 | 11 | 48:43 | 5 | 37 |
| 15 |
|
BV Veendam | 32 | 8 | 14 | 10 | 50:60 | -10 | 35 |
| 16 |
|
Fortuna Sittard | 32 | 9 | 8 | 15 | 41:54 | -13 | 35 |
| 17 |
|
SC Cambuur | 32 | 8 | 8 | 16 | 41:57 | -16 | 32 |
| 18 |
|
AGOVV | 32 | 10 | 5 | 17 | 54:82 | -28 | 32 |
| 19 |
|
FC Eindhoven | 32 | 7 | 8 | 17 | 40:68 | -28 | 29 |
| 20 |
|
HFC Haarlem | 32 | 5 | 12 | 15 | 34:48 | -14 | 27 |
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