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| 21.03.2008 | 20:00 | BV Veendam | - | Fortuna Sittard | 3:1 (2:1) | |
| 20:00 | SC Cambuur | - | FC Den Bosch | 0:2 (0:2) | ||
| 20:00 | FC Volendam | - | TOP Oss | 3:0 (2:0) | ||
| 20:00 | Helmond Sport | - | RKC Waalwijk | 3:3 (2:2) | ||
| 20:00 | MVV | - | FC Emmen | 5:1 (4:1) | ||
| 20:00 | FC Zwolle | - | Stormvogels Telstar | 1:0 (0:0) | ||
| 20:00 | ADO Den Haag | - | HFC Haarlem | 2:1 (0:0) | ||
| 20:00 | RBC Roosendaal | - | FC Dordrecht | 1:2 (1:0) | ||
| 20:00 | FC Omniworld | - | FC Eindhoven | 3:1 (2:1) | ||
| 23.03.2008 | 14:30 | AGOVV | - | Go Ahead Eagles | 2:0 (2:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Volendam | 34 | 18 | 11 | 5 | 79:42 | 37 | 65 |
| 2 |
|
RKC Waalwijk | 34 | 18 | 11 | 5 | 78:43 | 35 | 65 |
| 3 |
|
FC Zwolle | 34 | 17 | 12 | 5 | 66:37 | 29 | 63 |
| 4 |
|
FC Den Bosch | 34 | 18 | 7 | 9 | 54:36 | 18 | 61 |
| 5 |
|
ADO Den Haag | 34 | 16 | 9 | 9 | 55:44 | 11 | 57 |
| 6 |
|
MVV | 34 | 15 | 9 | 10 | 59:46 | 13 | 54 |
| 7 |
|
Helmond Sport | 34 | 16 | 6 | 12 | 50:44 | 6 | 54 |
| 8 |
|
RBC Roosendaal | 34 | 12 | 10 | 12 | 43:43 | 0 | 46 |
| 9 |
|
FC Dordrecht | 34 | 11 | 11 | 12 | 58:48 | 10 | 44 |
| 10 |
|
Go Ahead Eagles | 34 | 14 | 2 | 18 | 51:59 | -8 | 44 |
| 11 |
|
FC Omniworld | 34 | 10 | 13 | 11 | 53:45 | 8 | 43 |
| 12 |
|
Stormvogels Telstar | 34 | 13 | 4 | 17 | 38:44 | -6 | 43 |
| 13 |
|
TOP Oss | 34 | 11 | 10 | 13 | 48:59 | -11 | 43 |
| 14 |
|
FC Emmen | 34 | 11 | 10 | 13 | 53:69 | -16 | 43 |
| 15 |
|
BV Veendam | 34 | 10 | 14 | 10 | 54:61 | -7 | 41 |
| 16 |
|
Fortuna Sittard | 34 | 9 | 8 | 17 | 42:64 | -22 | 35 |
| 17 |
|
AGOVV | 34 | 11 | 5 | 18 | 56:85 | -29 | 35 |
| 18 |
|
SC Cambuur | 34 | 8 | 8 | 18 | 41:62 | -21 | 32 |
| 19 |
|
FC Eindhoven | 34 | 7 | 8 | 19 | 41:72 | -31 | 29 |
| 20 |
|
HFC Haarlem | 34 | 5 | 12 | 17 | 35:51 | -16 | 27 |
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