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| 07.04.2018 | 00:00 | Tigre | - | Gimnasia de La Plata | 2:0 (1:0) | |
| 02:15 | Argentinos Juniors | - | Unión de Santa Fe | 3:1 (2:1) | ||
| 18:15 | Temperley | - | Lanús | 2:2 (1:1) | ||
| 18:15 | Rosario Central | - | Belgrano de Córdoba | 2:1 (2:0) | ||
| 22:45 | Banfield | - | Olimpo de Bahía Blanca | 3:0 (1:0) | ||
| 08.04.2018 | 01:00 | Boca Juniors | - | Defensa y Justicia | 1:2 (1:1) | |
| 16:00 | San Lorenzo | - | Godoy Cruz | 0:5 (0:4) | ||
| 18:15 | San Martín de San Juan | - | Huracán | 0:1 (0:1) | ||
| 20:30 | Atlético Tucumán | - | Newell's Old Boys | 1:1 (1:0) | ||
| 22:45 | Talleres de Córdoba | - | Independiente | 0:2 (0:1) | ||
| 09.04.2018 | 01:00 | Racing Club | - | River Plate | 0:2 (0:0) | |
| 10.04.2018 | 00:00 | Arsenal de Sarandí | - | Patronato de Paraná | 1:1 (1:0) | |
| 02:15 | Estudiantes | - | Chacarita Juniors | 0:2 (0:1) | ||
| 10.05.2018 | 22:45 | Colón de Santa Fe | - | Vélez Sarsfield | 0:1 (0:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Boca Juniors | 22 | 16 | 2 | 4 | 40:15 | 25 | 50 |
| 2 |
|
Godoy Cruz | 22 | 13 | 4 | 5 | 35:22 | 13 | 43 |
| 3 |
|
San Lorenzo | 22 | 12 | 6 | 4 | 26:16 | 10 | 42 |
| 4 |
|
Talleres de Córdoba | 22 | 12 | 5 | 5 | 28:13 | 15 | 41 |
| 5 |
|
Independiente | 22 | 11 | 6 | 5 | 25:15 | 10 | 39 |
| 6 |
|
Huracán | 22 | 10 | 7 | 5 | 26:19 | 7 | 37 |
| 7 |
|
Racing Club | 22 | 10 | 6 | 6 | 37:25 | 12 | 36 |
| 8 |
|
Argentinos Juniors | 22 | 11 | 3 | 8 | 33:26 | 7 | 36 |
| 9 |
|
Unión de Santa Fe | 22 | 9 | 8 | 5 | 26:18 | 8 | 35 |
| 10 |
|
River Plate | 22 | 9 | 5 | 8 | 30:26 | 4 | 32 |
| 11 |
|
Defensa y Justicia | 22 | 9 | 5 | 8 | 32:30 | 2 | 32 |
| 12 |
|
Estudiantes | 22 | 9 | 5 | 8 | 22:20 | 2 | 32 |
| 13 |
|
Colón de Santa Fe | 22 | 8 | 7 | 7 | 23:20 | 3 | 31 |
| 14 |
|
Rosario Central | 22 | 8 | 7 | 7 | 28:29 | -1 | 31 |
| 15 |
|
Belgrano de Córdoba | 22 | 7 | 10 | 5 | 22:23 | -1 | 31 |
| 16 |
|
Atlético Tucumán | 22 | 7 | 9 | 6 | 24:21 | 3 | 30 |
| 17 |
|
Banfield | 22 | 8 | 5 | 9 | 24:21 | 3 | 29 |
| 18 |
|
Patronato de Paraná | 22 | 7 | 7 | 8 | 24:26 | -2 | 28 |
| 19 |
|
Vélez Sarsfield | 22 | 7 | 6 | 9 | 21:27 | -6 | 27 |
| 20 |
|
San Martín de San Juan | 22 | 7 | 5 | 10 | 23:30 | -7 | 26 |
| 21 |
|
Lanús | 22 | 6 | 6 | 10 | 19:36 | -17 | 24 |
| 22 |
|
Gimnasia de La Plata | 22 | 6 | 4 | 12 | 21:35 | -14 | 22 |
| 23 |
|
Newell's Old Boys | 22 | 6 | 6 | 10 | 19:21 | -2 | 21 |
| 24 |
|
Tigre | 22 | 3 | 10 | 9 | 18:25 | -7 | 19 |
| 25 |
|
Chacarita Juniors | 22 | 4 | 6 | 12 | 20:29 | -9 | 18 |
| 26 |
|
Temperley | 22 | 3 | 8 | 11 | 14:34 | -20 | 17 |
| 27 |
|
Arsenal de Sarandí | 22 | 2 | 8 | 12 | 15:26 | -11 | 14 |
| 28 |
|
Olimpo de Bahía Blanca | 22 | 3 | 4 | 15 | 12:39 | -27 | 13 |
| Copa Libertadores | |
| Copa Sudamericana |
