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| 02.04.2021 | 22:00 | Patronato de Paraná | - | Aldosivi | 2:0 (1:0) | |
| 03.04.2021 | 00:00 | San Lorenzo | - | Rosario Central | 2:0 (1:0) | |
| 02:15 | Central Córdoba SdE | - | Platense | 0:1 (0:0) | ||
| 19:00 | Talleres de Córdoba | - | Independiente | 3:1 (2:0) | ||
| 21:15 | Gimnasia de La Plata | - | Lanús | 2:4 (1:2) | ||
| 21:15 | Sarmiento de Junín | - | Atlético Tucumán | 1:2 (1:0) | ||
| 23:30 | Boca Juniors | - | Defensa y Justicia | 2:1 (1:1) | ||
| 04.04.2021 | 02:00 | Arsenal de Sarandí | - | River Plate | 0:0 (0:0) | |
| 19:00 | Newell's Old Boys | - | Huracán | 2:2 (2:1) | ||
| 21:15 | Colón de Santa Fe | - | Argentinos Juniors | 0:0 (0:0) | ||
| 23:30 | Vélez Sarsfield | - | Unión de Santa Fe | 4:1 (2:1) | ||
| 05.04.2021 | 02:00 | Racing Club | - | Godoy Cruz | 2:4 (0:2) | |
| 06.04.2021 | 02:15 | Banfield | - | Estudiantes | 2:2 (0:2) |
| 1 | |||||||||
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Colón de Santa Fe | 8 | 6 | 2 | 0 | 15:2 | 13 | 20 |
| 2 |
|
Banfield | 8 | 3 | 4 | 1 | 10:7 | 3 | 13 |
| 3 |
|
River Plate | 8 | 3 | 3 | 2 | 12:5 | 7 | 12 |
| 4 |
|
Estudiantes | 8 | 3 | 3 | 2 | 12:8 | 4 | 12 |
| 5 |
|
Central Córdoba SdE | 8 | 3 | 3 | 2 | 12:10 | 2 | 12 |
| 6 |
|
Racing Club | 8 | 3 | 3 | 2 | 8:8 | 0 | 12 |
| 7 |
|
San Lorenzo | 8 | 3 | 2 | 3 | 8:10 | -2 | 11 |
| 8 |
|
Godoy Cruz | 8 | 3 | 2 | 3 | 13:17 | -4 | 11 |
| 9 |
|
Argentinos Juniors | 8 | 3 | 1 | 4 | 7:8 | -1 | 10 |
| 10 |
|
Rosario Central | 8 | 2 | 3 | 3 | 8:12 | -4 | 9 |
| 11 |
|
Aldosivi | 8 | 2 | 2 | 4 | 11:12 | -1 | 8 |
| 12 |
|
Platense | 8 | 2 | 2 | 4 | 5:10 | -5 | 8 |
| 13 |
|
Arsenal de Sarandí | 8 | 0 | 2 | 6 | 4:17 | -13 | 2 |
| 2 | |||||||||
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Vélez Sarsfield | 8 | 6 | 1 | 1 | 13:10 | 3 | 19 |
| 2 |
|
Lanús | 8 | 5 | 1 | 2 | 15:11 | 4 | 16 |
| 3 |
|
Boca Juniors | 8 | 3 | 4 | 1 | 16:9 | 7 | 13 |
| 4 |
|
Independiente | 8 | 4 | 1 | 3 | 12:7 | 5 | 13 |
| 5 |
|
Talleres de Córdoba | 8 | 3 | 3 | 2 | 10:10 | 0 | 12 |
| 6 |
|
Defensa y Justicia | 8 | 3 | 2 | 3 | 13:11 | 2 | 11 |
| 7 |
|
Unión de Santa Fe | 8 | 2 | 5 | 1 | 9:10 | -1 | 11 |
| 8 |
|
Gimnasia de La Plata | 8 | 2 | 4 | 2 | 12:10 | 2 | 10 |
| 9 |
|
Huracán | 8 | 1 | 6 | 1 | 9:9 | 0 | 9 |
| 10 |
|
Atlético Tucumán | 8 | 2 | 3 | 3 | 13:14 | -1 | 9 |
| 11 |
|
Sarmiento de Junín | 8 | 1 | 4 | 3 | 8:14 | -6 | 7 |
| 12 |
|
Newell's Old Boys | 8 | 0 | 4 | 4 | 7:14 | -7 | 4 |
| 13 |
|
Patronato de Paraná | 8 | 1 | 0 | 7 | 6:13 | -7 | 3 |
| Play-off | |
| Play-off |
