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| 19.10.2018 | 17:00 | Pumas UNAM II | - | Real Zamora | 2:1 (2:1) | |
| 17:00 | CF América II | - | Sporting Canamy | 3:1 (3:1) | ||
| 20.10.2018 | 02:30 | Atlético Reynosa | - | Murciélagos FC | 1:2 (1:2) | |
| 02:30 | Dorados UACH | - | Tepatitlán | 1:1 (1:1) | ||
| 03:00 | Alacranes de Durango | - | Monarcas Morelia II | 0:1 (0:1) | ||
| 19:15 | Deportivo Toluca II | - | Cruz Azul Hidalgo | 2:2 (2:2) | ||
| 23:00 | Albinegros Orizaba | - | Cocodrilos de Tabasco | 1:0 (1:0) | ||
| 23:00 | Tuxtla FC | - | Club Irapuato | 0:2 (0:2) | ||
| 23:00 | Loros UCOL | - | Leones Negros II | 3:0 (3:0) | ||
| 21.10.2018 | 00:00 | Correcaminos UAT II | - | Tecos Fútbol Club | 1:2 (1:2) | |
| 00:00 | Pioneros de Cancún | - | Yalmakan FC | 0:3 (0:3) | ||
| 00:00 | Pacific F. C. | - | Gavilanes de Matamoros | 0:3 (0:3) | ||
| 01:00 | Coras de Nayarit | - | Club Necaxa II | 0:2 (0:2) | ||
| 02:00 | Inter Playa | - | Tuzos de la UAZ | 0:1 (0:1) | ||
| 17:00 | Deportivo Guadalajara II | - | Cimarrones de Sonora II | 5:1 (5:1) | ||
| 23.10.2018 | 00:00 | Coyotes de Tlaxcala | - | Reboceros de La Piedad | 1:2 (1:2) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Club Irapuato | 9 | 8 | 0 | 1 | 19:7 | 12 | 28 |
| 2 |
|
Deportivo Guadalajara II | 9 | 6 | 2 | 1 | 16:6 | 10 | 24 |
| 3 |
|
Gavilanes de Matamoros | 9 | 6 | 1 | 2 | 16:9 | 7 | 21 |
| 4 |
|
Loros UCOL | 9 | 4 | 2 | 3 | 18:9 | 9 | 20 |
| 5 |
|
Murciélagos FC | 9 | 5 | 2 | 2 | 15:9 | 6 | 20 |
| 6 |
|
Deportivo Toluca II | 9 | 4 | 5 | 0 | 19:13 | 6 | 19 |
| 7 |
|
Tepatitlán | 9 | 5 | 2 | 2 | 14:10 | 4 | 19 |
| 8 |
|
Club Necaxa II | 9 | 4 | 4 | 1 | 9:7 | 2 | 19 |
| 9 |
|
Tuxtla FC | 9 | 5 | 1 | 3 | 17:10 | 7 | 18 |
| 10 |
|
Inter Playa | 9 | 5 | 1 | 3 | 15:11 | 4 | 18 |
| 11 |
|
Tuzos de la UAZ | 9 | 4 | 4 | 1 | 14:11 | 3 | 18 |
| 12 |
|
Cruz Azul Hidalgo | 9 | 4 | 2 | 3 | 13:10 | 3 | 18 |
| 13 |
|
Coras de Nayarit | 9 | 4 | 3 | 2 | 12:10 | 2 | 17 |
| 14 |
|
Correcaminos UAT II | 9 | 3 | 4 | 2 | 12:9 | 3 | 16 |
| 15 |
|
Dorados UACH | 9 | 3 | 3 | 3 | 9:12 | -3 | 16 |
| 16 |
|
Pumas UNAM II | 9 | 4 | 0 | 5 | 12:11 | 1 | 15 |
| 17 |
|
Coyotes de Tlaxcala | 9 | 3 | 3 | 3 | 10:10 | 0 | 14 |
| 18 |
|
Monarcas Morelia II | 9 | 3 | 3 | 3 | 17:7 | 10 | 13 |
| 19 |
|
Albinegros Orizaba | 9 | 3 | 3 | 3 | 5:6 | -1 | 13 |
| 20 |
|
Reboceros de La Piedad | 9 | 2 | 3 | 4 | 10:14 | -4 | 13 |
| 21 |
|
Tecos Fútbol Club | 9 | 2 | 2 | 5 | 8:14 | -6 | 13 |
| 22 |
|
CF América II | 9 | 2 | 4 | 3 | 12:16 | -4 | 12 |
| 23 |
|
Yalmakan FC | 9 | 2 | 3 | 4 | 8:9 | -1 | 11 |
| 24 |
|
Real Zamora | 9 | 3 | 0 | 6 | 11:17 | -6 | 11 |
| 25 |
|
Pacific F. C. | 9 | 2 | 3 | 4 | 11:21 | -10 | 11 |
| 26 |
|
Leones Negros II | 9 | 2 | 3 | 4 | 15:16 | -1 | 10 |
| 27 |
|
Atlético Reynosa | 9 | 1 | 3 | 5 | 8:10 | -2 | 10 |
| 28 |
|
Cocodrilos de Tabasco | 9 | 1 | 3 | 5 | 10:14 | -4 | 9 |
| 29 |
|
Pioneros de Cancún | 9 | 1 | 4 | 4 | 10:16 | -6 | 9 |
| 30 |
|
Sporting Canamy | 9 | 2 | 2 | 5 | 10:20 | -10 | 9 |
| 31 |
|
Alacranes de Durango | 9 | 1 | 3 | 5 | 6:16 | -10 | 7 |
| 32 |
|
Cimarrones de Sonora II | 9 | 0 | 2 | 7 | 5:26 | -21 | 2 |
| Play-off | |
| Play-off | |
| Play-off | |
| Play-off | |
| Play-off | |
| Play-off | |
| Play-off | |
| Play-off | |
| Play-off | |
| Relégation |
