 |
 |
|
|
| 19.03.2021 | 03:00 | CF Pachuca | - | UANL Tigres | 1:0 (0:0) | |
| 20.03.2021 | 02:00 | Club Necaxa | - | FC Juárez | 1:0 (0:0) | |
| 04:00 | Mazatlán FC | - | CF América | 0:1 (0:0) | ||
| 21.03.2021 | 00:00 | Atlético San Luis | - | Pumas UNAM | 0:1 (0:0) | |
| 02:00 | Cruz Azul | - | Atlas Guadalajara | 3:2 (1:1) | ||
| 04:05 | Club Tijuana | - | Gallos Blancos | 3:1 (3:1) | ||
| 19:00 | Deportivo Toluca | - | Puebla FC | 4:4 (1:0) | ||
| 22.03.2021 | 02:06 | Santos Laguna | - | Club León | 1:2 (1:1) | |
| 22.04.2021 | 04:10 | CF Monterrey | - | Deportivo Guadalajara | 1:2 (0:1) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Cruz Azul | 12 | 10 | 0 | 2 | 19:7 | 12 | 30 |
| 2 |
|
CF América | 12 | 9 | 1 | 2 | 18:8 | 10 | 28 |
| 3 |
|
Santos Laguna | 12 | 6 | 3 | 3 | 14:9 | 5 | 21 |
| 4 |
|
CF Monterrey | 12 | 5 | 4 | 3 | 16:9 | 7 | 19 |
| 5 |
|
Deportivo Toluca | 12 | 5 | 4 | 3 | 20:15 | 5 | 19 |
| 6 |
|
Atlas Guadalajara | 12 | 5 | 3 | 4 | 13:10 | 3 | 18 |
| 7 |
|
Puebla FC | 12 | 4 | 5 | 3 | 15:11 | 4 | 17 |
| 8 |
|
Club Tijuana | 12 | 4 | 4 | 4 | 15:14 | 1 | 16 |
| 9 |
|
UANL Tigres | 12 | 4 | 3 | 5 | 15:16 | -1 | 15 |
| 10 |
|
Deportivo Guadalajara | 12 | 3 | 6 | 3 | 17:19 | -2 | 15 |
| 11 |
|
Club León | 12 | 4 | 2 | 6 | 13:16 | -3 | 14 |
| 12 |
|
Gallos Blancos | 12 | 4 | 2 | 6 | 16:22 | -6 | 14 |
| 13 |
|
Mazatlán FC | 12 | 4 | 2 | 6 | 11:17 | -6 | 14 |
| 14 |
|
CF Pachuca | 12 | 3 | 4 | 5 | 10:13 | -3 | 13 |
| 15 |
|
Atlético San Luis | 12 | 3 | 3 | 6 | 15:17 | -2 | 12 |
| 16 |
|
Pumas UNAM | 12 | 3 | 3 | 6 | 7:9 | -2 | 12 |
| 17 |
|
Club Necaxa | 12 | 2 | 4 | 6 | 12:20 | -8 | 10 |
| 18 |
|
FC Juárez | 12 | 2 | 3 | 7 | 10:24 | -14 | 9 |
| Play-off | |
| Play-off |
