 |
 |
|
|
| 23.04.2021 | 18:45 | Puebla FC | - | Pumas UNAM | 2:8 (0:5) | |
| 21:45 | Club Tijuana | - | Club Necaxa | 0:0 (0:0) | ||
| 24.04.2021 | 16:00 | Cruz Azul | - | Atlético San Luis | 5:0 (1:0) | |
| 17:00 | Mazatlán FC | - | Club León | 1:1 (1:1) | ||
| 18:00 | UANL Tigres | - | CF Monterrey | 2:1 (0:0) | ||
| 18:30 | Atlas Guadalajara | - | Deportivo Guadalajara | 1:0 (0:0) | ||
| 25.04.2021 | 18:30 | Deportivo Toluca | - | CF América | 3:0 (1:0) | |
| 18:30 | Gallos Blancos | - | FC Juárez | 0:0 (0:0) | ||
| 26.04.2021 | 16:30 | CF Pachuca | - | Santos Laguna | 4:2 (2:1) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF Pachuca | 16 | 11 | 3 | 2 | 48:24 | 24 | 49 |
| 2 |
|
Atlas Guadalajara | 16 | 10 | 2 | 4 | 27:18 | 9 | 44 |
| 3 |
|
Club León | 16 | 9 | 5 | 2 | 30:17 | 13 | 39 |
| 4 |
|
UANL Tigres | 16 | 8 | 4 | 4 | 26:21 | 5 | 35 |
| 5 |
|
Pumas UNAM | 16 | 8 | 2 | 6 | 32:20 | 12 | 34 |
| 6 |
|
Santos Laguna | 16 | 7 | 4 | 5 | 29:26 | 3 | 34 |
| 7 |
|
Deportivo Guadalajara | 16 | 7 | 5 | 4 | 27:18 | 9 | 33 |
| 8 |
|
Cruz Azul | 16 | 8 | 1 | 7 | 29:24 | 5 | 33 |
| 9 |
|
Club Tijuana | 16 | 7 | 3 | 6 | 24:22 | 2 | 33 |
| 10 |
|
Deportivo Toluca | 16 | 6 | 6 | 4 | 25:20 | 5 | 32 |
| 11 |
|
Club Necaxa | 16 | 6 | 3 | 7 | 26:21 | 5 | 31 |
| 12 |
|
CF Monterrey | 16 | 6 | 2 | 8 | 24:25 | -1 | 27 |
| 13 |
|
FC Juárez | 16 | 6 | 2 | 8 | 19:21 | -2 | 27 |
| 14 |
|
Mazatlán FC | 16 | 4 | 5 | 7 | 17:28 | -11 | 27 |
| 15 |
|
Puebla FC | 16 | 5 | 3 | 8 | 25:34 | -9 | 25 |
| 16 |
|
Atlético San Luis | 16 | 2 | 2 | 12 | 13:45 | -32 | 20 |
| 17 |
|
Gallos Blancos | 16 | 3 | 3 | 10 | 17:33 | -16 | 18 |
| 18 |
|
CF América | 16 | 3 | 1 | 12 | 18:39 | -21 | 16 |
| Play-off |
