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| 13.08.2021 | Sputnik Rechytsa | - | Energetik-BGU Minsk | 0:3 | ||
| 18:00 | Rukh Brest | - | FK Isloch Minsk | 7:1 (3:0) | ||
| 14.08.2021 | 14:30 | FK Vitebsk | - | FK Slaviya Mozyr | 2:2 (0:1) | |
| 16:30 | Torpedo-BelAZ Zhodino | - | FK Slutsk | 0:1 (0:0) | ||
| 18:30 | Dinamo Minsk | - | Dinamo Brest | 2:0 (1:0) | ||
| 15.08.2021 | 14:30 | FK Smorgon | - | Shakhter Soligorsk | 2:2 (2:1) | |
| 17:30 | BATE Borisov | - | FK Minsk | 1:0 (0:0) | ||
| 19:30 | Neman Grodno | - | FK Gomel | 1:0 (1:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Shakhter Soligorsk | 19 | 17 | 2 | 0 | 43:11 | 32 | 53 |
| 2 |
|
BATE Borisov | 19 | 13 | 4 | 2 | 38:17 | 21 | 43 |
| 3 |
|
Dinamo Minsk | 19 | 12 | 3 | 4 | 35:13 | 22 | 39 |
| 4 |
|
Rukh Brest | 19 | 11 | 6 | 2 | 34:13 | 21 | 39 |
| 5 |
|
FK Gomel | 19 | 9 | 5 | 5 | 36:20 | 16 | 32 |
| 6 |
|
Dinamo Brest | 19 | 6 | 9 | 4 | 22:15 | 7 | 27 |
| 7 |
|
Torpedo-BelAZ Zhodino | 19 | 7 | 4 | 8 | 19:25 | -6 | 25 |
| 8 |
|
FK Vitebsk | 19 | 5 | 9 | 5 | 22:18 | 4 | 24 |
| 9 |
|
FK Minsk | 19 | 6 | 6 | 7 | 25:30 | -5 | 24 |
| 10 |
|
Energetik-BGU Minsk | 19 | 6 | 5 | 8 | 24:25 | -1 | 23 |
| 11 |
|
FK Isloch Minsk | 19 | 5 | 5 | 9 | 23:35 | -12 | 20 |
| 12 |
|
FK Slutsk | 19 | 4 | 6 | 9 | 20:31 | -11 | 18 |
| 13 |
|
Neman Grodno | 19 | 4 | 6 | 9 | 17:26 | -9 | 18 |
| 14 |
|
FK Slaviya Mozyr | 19 | 3 | 5 | 11 | 21:36 | -15 | 14 |
| 15 |
|
FK Smorgon | 19 | 1 | 6 | 12 | 15:42 | -27 | 9 |
| 16 |
|
Sputnik Rechytsa | 19 | 2 | 1 | 16 | 12:49 | -37 | 7 |
| Champions League Quali. | |
| Relégation | |
| Relégation |
