 |
 |
|
|
| 16.04.2021 | 16:00 | Club Necaxa | - | Gallos Blancos | 4:1 (2:0) | |
| 17:00 | Mazatlán FC | - | Atlas Guadalajara | 2:2 (1:1) | ||
| 17.04.2021 | 16:00 | Deportivo Guadalajara | - | Club Tijuana | 2:1 (1:0) | |
| 17:00 | Atlético San Luis | - | Puebla FC | 5:3 (1:2) | ||
| 18:00 | CF América | - | Cruz Azul | 4:1 (3:1) | ||
| 18.04.2021 | 16:00 | Pumas UNAM | - | UANL Tigres | 2:4 (1:1) | |
| 16:00 | CF Monterrey | - | CF Pachuca | 2:1 (1:0) | ||
| 18:00 | Santos Laguna | - | Deportivo Toluca | 2:2 (0:1) | ||
| 19.04.2021 | 16:00 | Club León | - | FC Juárez | 1:2 (1:1) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF Pachuca | 15 | 9 | 4 | 2 | 34:19 | 15 | 31 |
| 2 |
|
CF Monterrey | 15 | 10 | 1 | 4 | 26:16 | 10 | 31 |
| 3 |
|
CF América | 15 | 8 | 3 | 4 | 26:13 | 13 | 27 |
| 4 |
|
Deportivo Toluca | 15 | 8 | 3 | 4 | 29:18 | 11 | 27 |
| 5 |
|
Club Tijuana | 15 | 8 | 1 | 6 | 22:15 | 7 | 25 |
| 6 |
|
Atlas Guadalajara | 15 | 7 | 3 | 5 | 20:15 | 5 | 24 |
| 7 |
|
Mazatlán FC | 15 | 6 | 4 | 5 | 25:25 | 0 | 22 |
| 8 |
|
FC Juárez | 15 | 6 | 4 | 5 | 17:19 | -2 | 22 |
| 9 |
|
UANL Tigres | 15 | 6 | 3 | 6 | 24:17 | 7 | 21 |
| 10 |
|
Santos Laguna | 15 | 5 | 5 | 5 | 24:18 | 6 | 20 |
| 11 |
|
Club León | 15 | 6 | 2 | 7 | 20:28 | -8 | 20 |
| 12 |
|
Deportivo Guadalajara | 15 | 6 | 1 | 8 | 25:25 | 0 | 19 |
| 13 |
|
Puebla FC | 15 | 6 | 0 | 9 | 29:38 | -9 | 18 |
| 14 |
|
Pumas UNAM | 15 | 4 | 4 | 7 | 22:30 | -8 | 16 |
| 15 |
|
Atlético San Luis | 15 | 5 | 1 | 9 | 22:34 | -12 | 16 |
| 16 |
|
Club Necaxa | 15 | 4 | 3 | 8 | 16:21 | -5 | 15 |
| 17 |
|
Cruz Azul | 15 | 4 | 3 | 8 | 11:25 | -14 | 15 |
| 18 |
|
Gallos Blancos | 15 | 4 | 1 | 10 | 13:29 | -16 | 13 |
| Play-off |
