 |
 |
|
|
| 30.07.2021 | 16:00 | Puebla FC | - | Deportivo Guadalajara | 3:1 (2:0) | |
| 17:00 | Mazatlán FC | - | CF Pachuca | 1:1 (0:1) | ||
| 31.07.2021 | 16:00 | CF América | - | Club Necaxa | 3:1 (1:0) | |
| 16:00 | Atlas Guadalajara | - | FC Juárez | 2:1 (1:0) | ||
| 16:00 | Club León | - | Club Tijuana | 2:1 (1:0) | ||
| 16:00 | CF Monterrey | - | Pumas UNAM | 3:1 (1:0) | ||
| 01.08.2021 | 16:00 | Deportivo Toluca | - | UANL Tigres | 2:0 (1:0) | |
| 18:00 | Santos Laguna | - | Cruz Azul | 1:0 (1:0) | ||
| 02.08.2021 | 16:00 | Atlético San Luis | - | Gallos Blancos | 0:2 (0:1) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF Monterrey | 2 | 2 | 0 | 0 | 7:2 | 5 | 6 |
| 2 |
|
CF América | 2 | 2 | 0 | 0 | 4:1 | 3 | 6 |
| 3 |
|
Deportivo Toluca | 2 | 2 | 0 | 0 | 3:0 | 3 | 6 |
| 4 |
|
Club León | 2 | 2 | 0 | 0 | 3:1 | 2 | 6 |
| 5 |
|
Atlético San Luis | 2 | 1 | 0 | 1 | 5:3 | 2 | 3 |
| 6 |
|
Club Necaxa | 2 | 1 | 0 | 1 | 4:3 | 1 | 3 |
| 7 |
|
Gallos Blancos | 2 | 1 | 0 | 1 | 2:1 | 1 | 3 |
| 8 |
|
Atlas Guadalajara | 2 | 1 | 0 | 1 | 2:2 | 0 | 3 |
| 9 |
|
Puebla FC | 2 | 1 | 0 | 1 | 4:5 | -1 | 3 |
| 10 |
|
Pumas UNAM | 2 | 1 | 0 | 1 | 2:3 | -1 | 3 |
| 11 |
|
Santos Laguna | 2 | 1 | 0 | 1 | 1:3 | -2 | 3 |
| 12 |
|
Mazatlán FC | 2 | 0 | 2 | 0 | 2:2 | 0 | 2 |
| 13 |
|
Club Tijuana | 2 | 0 | 1 | 1 | 2:3 | -1 | 1 |
| 14 |
|
CF Pachuca | 2 | 0 | 1 | 1 | 1:2 | -1 | 1 |
|
Cruz Azul | 2 | 0 | 1 | 1 | 1:2 | -1 | 1 | |
| 16 |
|
UANL Tigres | 2 | 0 | 1 | 1 | 1:3 | -2 | 1 |
| 17 |
|
FC Juárez | 2 | 0 | 0 | 2 | 1:3 | -2 | 0 |
| 18 |
|
Deportivo Guadalajara | 2 | 0 | 0 | 2 | 2:8 | -6 | 0 |
| Play-off |
