 |
 |
|
|
| 05.08.2021 | 16:00 | Gallos Blancos | - | Club León | 1:0 (1:0) | |
| 06.08.2021 | 16:00 | Club Necaxa | - | Cruz Azul | 1:0 (0:0) | |
| 17:00 | Mazatlán FC | - | CF Monterrey | 1:4 (1:4) | ||
| 07.08.2021 | 00:45 | Club Tijuana | - | Deportivo Toluca | 1:0 (1:0) | |
| 16:00 | CF América | - | Puebla FC | 3:3 (0:3) | ||
| 16:00 | Deportivo Guadalajara | - | FC Juárez | 0:0 (0:0) | ||
| 16:00 | UANL Tigres | - | Santos Laguna | 1:1 (0:1) | ||
| 08.08.2021 | 16:00 | Pumas UNAM | - | Atlético San Luis | 5:3 (2:1) | |
| 09.08.2021 | 19:00 | CF Pachuca | - | Atlas Guadalajara | 1:1 (0:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF Monterrey | 3 | 3 | 0 | 0 | 11:3 | 8 | 9 |
| 2 |
|
CF América | 3 | 2 | 1 | 0 | 7:4 | 3 | 7 |
| 3 |
|
Club Necaxa | 3 | 2 | 0 | 1 | 5:3 | 2 | 6 |
| 4 |
|
Deportivo Toluca | 3 | 2 | 0 | 1 | 3:1 | 2 | 6 |
|
Gallos Blancos | 3 | 2 | 0 | 1 | 3:1 | 2 | 6 | |
| 6 |
|
Pumas UNAM | 3 | 2 | 0 | 1 | 7:6 | 1 | 6 |
| 7 |
|
Club León | 3 | 2 | 0 | 1 | 3:2 | 1 | 6 |
| 8 |
|
Atlas Guadalajara | 3 | 1 | 1 | 1 | 3:3 | 0 | 4 |
|
Club Tijuana | 3 | 1 | 1 | 1 | 3:3 | 0 | 4 | |
| 10 |
|
Puebla FC | 3 | 1 | 1 | 1 | 7:8 | -1 | 4 |
| 11 |
|
Santos Laguna | 3 | 1 | 1 | 1 | 2:4 | -2 | 4 |
| 12 |
|
Atlético San Luis | 3 | 1 | 0 | 2 | 8:8 | 0 | 3 |
| 13 |
|
CF Pachuca | 3 | 0 | 2 | 1 | 2:3 | -1 | 2 |
| 14 |
|
UANL Tigres | 3 | 0 | 2 | 1 | 2:4 | -2 | 2 |
| 15 |
|
Mazatlán FC | 3 | 0 | 2 | 1 | 3:6 | -3 | 2 |
| 16 |
|
Cruz Azul | 3 | 0 | 1 | 2 | 1:3 | -2 | 1 |
|
FC Juárez | 3 | 0 | 1 | 2 | 1:3 | -2 | 1 | |
| 18 |
|
Deportivo Guadalajara | 3 | 0 | 1 | 2 | 2:8 | -6 | 1 |
| Play-off |
