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| 01.01.2001 | 16:00 | Charlton Athletic | - | Arsenal FC | 1:0 (1:0) | |
| 16:00 | Chelsea FC | - | Aston Villa | 1:0 (1:0) | ||
| 16:00 | Coventry City | - | Manchester City | 1:1 (0:0) | ||
| 16:00 | Derby County | - | Everton FC | 1:0 (1:0) | ||
| 16:00 | Leeds United | - | Middlesbrough FC | 1:1 (0:1) | ||
| 16:00 | Leicester City | - | Bradford City | 1:2 (1:2) | ||
| 16:00 | Liverpool FC | - | Southampton FC | 2:1 (1:1) | ||
| 16:00 | Sunderland AFC | - | Ipswich Town | 4:1 (1:1) | ||
| 21:00 | Manchester United | - | West Ham United | 3:1 (2:0) | ||
| 02.01.2001 | 20:45 | Tottenham Hotspur | - | Newcastle United | 4:2 (3:1) |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Manchester United | 22 | 15 | 5 | 2 | 51:16 | 35 | 50 |
| 2 |
|
Arsenal FC | 22 | 11 | 6 | 5 | 38:22 | 16 | 39 |
| 3 |
|
Liverpool FC | 22 | 12 | 3 | 7 | 41:26 | 15 | 39 |
| 4 |
|
Sunderland AFC | 22 | 11 | 6 | 5 | 29:22 | 7 | 39 |
| 5 |
|
Ipswich Town | 22 | 11 | 4 | 7 | 33:26 | 7 | 37 |
| 6 |
|
Leicester City | 22 | 10 | 5 | 7 | 25:25 | 0 | 35 |
| 7 |
|
Chelsea FC | 22 | 9 | 6 | 7 | 40:27 | 13 | 33 |
| 8 |
|
Aston Villa | 22 | 8 | 8 | 6 | 26:22 | 4 | 32 |
| 9 |
|
Charlton Athletic | 22 | 9 | 4 | 9 | 31:36 | -5 | 31 |
| 10 |
|
Newcastle United | 22 | 9 | 4 | 9 | 25:30 | -5 | 31 |
| 11 |
|
Leeds United | 22 | 8 | 6 | 8 | 31:31 | 0 | 30 |
| 12 |
|
West Ham United | 22 | 7 | 8 | 7 | 31:26 | 5 | 29 |
| 13 |
|
Tottenham Hotspur | 22 | 8 | 5 | 9 | 30:34 | -4 | 29 |
| 14 |
|
Southampton FC | 22 | 7 | 6 | 9 | 28:34 | -6 | 27 |
| 15 |
|
Derby County | 22 | 5 | 8 | 9 | 24:36 | -12 | 23 |
| 16 |
|
Everton FC | 22 | 6 | 5 | 11 | 23:35 | -12 | 23 |
| 17 |
|
Coventry City | 22 | 5 | 6 | 11 | 21:37 | -16 | 21 |
| 18 |
|
Middlesbrough FC | 22 | 4 | 8 | 10 | 23:30 | -7 | 20 |
| 19 |
|
Manchester City | 22 | 5 | 5 | 12 | 27:38 | -11 | 20 |
| 20 |
|
Bradford City | 22 | 3 | 6 | 13 | 16:40 | -24 | 15 |
