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| 26.11.2010 | 20:30 | 1. FSV Mainz 05 | - | 1. FC Nürnberg | 3:0 (1:0) | |
| 27.11.2010 | 15:30 | Bayern München | - | Eintracht Frankfurt | 4:1 (1:1) | |
| 15:30 | Hamburger SV | - | VfB Stuttgart | 4:2 (3:1) | ||
| 15:30 | 1899 Hoffenheim | - | Bayer Leverkusen | 2:2 (1:2) | ||
| 15:30 | Hannover 96 | - | SC Freiburg | 3:0 (1:0) | ||
| 15:30 | 1. FC Kaiserslautern | - | FC Schalke 04 | 5:0 (2:0) | ||
| 18:30 | Borussia Dortmund | - | Bor. Mönchengladbach | 4:1 (1:1) | ||
| 28.11.2010 | 15:30 | Werder Bremen | - | FC St. Pauli | 3:0 (2:0) | |
| 17:30 | 1. FC Köln | - | VfL Wolfsburg | 1:1 (0:0) |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Borussia Dortmund | 14 | 12 | 1 | 1 | 35:9 | 26 | 37 |
| 2 |
|
1. FSV Mainz 05 | 14 | 10 | 0 | 4 | 25:14 | 11 | 30 |
| 3 |
|
Bayer Leverkusen | 14 | 7 | 5 | 2 | 26:19 | 7 | 26 |
| 4 |
|
Hannover 96 | 14 | 8 | 1 | 5 | 20:22 | -2 | 25 |
| 5 |
|
Bayern München | 14 | 6 | 5 | 3 | 23:15 | 8 | 23 |
| 6 |
|
1899 Hoffenheim | 14 | 6 | 4 | 4 | 28:18 | 10 | 22 |
| 7 |
|
Hamburger SV | 14 | 6 | 3 | 5 | 23:22 | 1 | 21 |
| 8 |
|
SC Freiburg | 14 | 7 | 0 | 7 | 19:23 | -4 | 21 |
| 9 |
|
Eintracht Frankfurt | 14 | 6 | 2 | 6 | 21:19 | 2 | 20 |
| 10 |
|
1. FC Nürnberg | 14 | 5 | 3 | 6 | 18:24 | -6 | 18 |
| 11 |
|
Werder Bremen | 14 | 5 | 3 | 6 | 22:31 | -9 | 18 |
| 12 |
|
1. FC Kaiserslautern | 14 | 5 | 2 | 7 | 25:25 | 0 | 17 |
| 13 |
|
VfL Wolfsburg | 14 | 4 | 4 | 6 | 22:23 | -1 | 16 |
| 14 |
|
FC St. Pauli | 14 | 4 | 2 | 8 | 13:23 | -10 | 14 |
| 15 |
|
FC Schalke 04 | 14 | 3 | 4 | 7 | 19:24 | -5 | 13 |
| 16 |
|
1. FC Köln | 14 | 3 | 3 | 8 | 15:27 | -12 | 12 |
| 17 |
|
VfB Stuttgart | 14 | 3 | 2 | 9 | 27:27 | 0 | 11 |
| 18 |
|
Bor. Mönchengladbach | 14 | 2 | 4 | 8 | 24:40 | -16 | 10 |
| Champions League | |
| Champions League Quali. | |
| Europa League | |
| Relégation | |
| Relégation |
