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| 09.09.2022 | 20:30 | Werder Bremen | - | FC Augsburg | 0:1 (0:0) | |
| 10.09.2022 | 15:30 | Bayern München | - | VfB Stuttgart | 2:2 (1:0) | |
| 15:30 | RB Leipzig | - | Borussia Dortmund | 3:0 (2:0) | ||
| 15:30 | 1899 Hoffenheim | - | 1. FSV Mainz 05 | 4:1 (0:0) | ||
| 15:30 | Eintracht Frankfurt | - | VfL Wolfsburg | 0:1 (0:0) | ||
| 15:30 | Hertha BSC | - | Bayer Leverkusen | 2:2 (0:0) | ||
| 18:30 | FC Schalke 04 | - | VfL Bochum | 3:1 (1:0) | ||
| 11.09.2022 | 15:30 | 1. FC Köln | - | 1. FC Union Berlin | 0:1 (0:1) | |
| 17:30 | SC Freiburg | - | Bor. Mönchengladbach | 0:0 (0:0) |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
1. FC Union Berlin | 6 | 4 | 2 | 0 | 13:4 | 9 | 14 |
| 2 |
|
SC Freiburg | 6 | 4 | 1 | 1 | 10:5 | 5 | 13 |
| 3 |
|
Bayern München (M) | 6 | 3 | 3 | 0 | 19:5 | 14 | 12 |
| 4 |
|
1899 Hoffenheim | 6 | 4 | 0 | 2 | 12:7 | 5 | 12 |
| 5 |
|
Borussia Dortmund | 6 | 4 | 0 | 2 | 8:7 | 1 | 12 |
| 6 |
|
1. FSV Mainz 05 | 6 | 3 | 1 | 2 | 6:9 | -3 | 10 |
| 7 |
|
1. FC Köln | 6 | 2 | 3 | 1 | 10:7 | 3 | 9 |
| 8 |
|
Bor. Mönchengladbach | 6 | 2 | 3 | 1 | 7:5 | 2 | 9 |
| 9 |
|
Werder Bremen (N) | 6 | 2 | 2 | 2 | 12:11 | 1 | 8 |
| 10 |
|
RB Leipzig (P) | 6 | 2 | 2 | 2 | 9:9 | 0 | 8 |
| 11 |
|
Eintracht Frankfurt | 6 | 2 | 2 | 2 | 11:12 | -1 | 8 |
| 12 |
|
FC Schalke 04 (N) | 6 | 1 | 3 | 2 | 8:13 | -5 | 6 |
| 13 |
|
FC Augsburg | 6 | 2 | 0 | 4 | 4:10 | -6 | 6 |
| 14 |
|
VfB Stuttgart | 6 | 0 | 5 | 1 | 6:7 | -1 | 5 |
| 15 |
|
Hertha BSC | 6 | 1 | 2 | 3 | 6:8 | -2 | 5 |
| 16 |
|
VfL Wolfsburg | 6 | 1 | 2 | 3 | 5:10 | -5 | 5 |
| 17 |
|
Bayer Leverkusen | 6 | 1 | 1 | 4 | 8:11 | -3 | 4 |
| 18 |
|
VfL Bochum | 6 | 0 | 0 | 6 | 4:18 | -14 | 0 |
| Champions League | |
| Europa League | |
| Relégation | |
| Relégation |
